Mono-(2-ethylhexyl) phthalate (MEHP) is the active metabolite of the most commonly used plasticizer, di-(2-ethylhexyl) phthalate, and is considered to be a reproductive toxicant. However, little is known about the effects of MEHP on ovarian antral follicles.
Thus, the present study tested the hypothesis that MEHP inhibits follicle growth via oxidative stress pathways. The data indicate that MEHP increases reactive oxygen species (ROS) levels and inhibits follicle growth in antral follicles, whereas N-acetylcysteine (NAC; an antioxidant) restores ROS levels to control levels and rescues follicles from MEHP-induced inhibition of follicle growth.
To further analyze the mechanism by which MEHP induces oxidative stress and inhibits follicle growth, the expression and activities of various key antioxidant enzymes (copper/zinc superoxide dismutase [SOD1], glutathione peroxidase [GPX], and catalase [CAT]) and the expression of key cell-cycle regulators (Ccnd2, Ccne1, and Cdk4) and apoptotic regulators (Bcl-2 and Bax) were compared in control and MEHP-treated follicles.
The data indicate that MEHP inhibits the expression and activities of SOD1 and GPX; does not inhibit Cat expression; inhibits the expression of Ccnd2, Ccne1, Cdk4, and Bcl-2; but increases the expression of Bax compared to controls. Furthermore, NAC blocks these toxic effects of MEHP.
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Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-10ug
QP8982-ye-10ug EnQuireBio 10ug 369.6 EUR ![]()
Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-50ug
QP8982-ye-50ug EnQuireBio 50ug 500.4 EUR ![]()
Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-100ug
QP8982-ye-100ug EnQuireBio 100ug 804 EUR ![]()
Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-200ug
QP8982-ye-200ug EnQuireBio 200ug 1282.8 EUR ![]()
Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-500ug
QP8982-ye-500ug EnQuireBio 500ug 2164.8 EUR ![]()
Annexin VII (Annexin VII) Antibody
abx230439-100ug Abbexa 100 ug 610.8 EUR ![]()
Horse ANX5(Annexin 5) ELISA Kit
EHS0047 FN Test 96T 681.12 EUR Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Horse;Sensitivity: 0.938 ng/ml![]()
Annexin VIII (Annexin VIII) Antibody
abx230440-100ug Abbexa 100 ug 577.2 EUR ![]()
Annexin VI/Annexin A6 Rabbit pAb
E2382616 EnoGene 100ul 225 EUR Description: Available in various conjugation types.![]()
Annexin A4/Annexin IV Rabbit mAb
A9203 Abclonal 50μL 1557.4 EUR Description: A synthetic peptide of human CD62P/P-selectin.![]()
Annexin A5/Annexin V Rabbit mAb
A9262 Abclonal 200μL 213.2 EUR Description: Recombinant fusion protein containing a sequence corresponding to amino acids 165-225 of human CD79a (NP_001774.1).![]()
Annexin A6/Annexin VI Rabbit mAb
A22038 Abclonal 500μL 83.2 EUR Description: Recombinant protein of Human PMF1.![]()
Annexin V 647
E16FXP023a-100T EnoGene 100 tests 433.33 EUR Description: Available in various conjugation types.![]()
Annexin A1
PR27207 Neuromics 2 ug 465.6 EUR ![]()
Annexin A2
PR27211 Neuromics 5 ug 229.2 EUR ![]()
Annexin A3
PR27212 Neuromics 5 ug 229.2 EUR ![]()
Annexin A4
PR27213 Neuromics 2 ug 229.2 EUR ![]()
Annexin A5
PR27214 Neuromics 5 ug 229.2 EUR ![]()
Annexin A6
PR27215 Neuromics 2 ug 229.2 EUR ![]()
Annexin A7
PR27216 Neuromics 5 ug 229.2 EUR ![]()
Annexin A8
PR27217 Neuromics 5 ug 229.2 EUR ![]()
Annexin A3
E8ER1802-50 EnoGene 100ul 275 EUR Description: Available in various conjugation types.![]()
Annexin A1
E8ER1803-70 EnoGene 100ul 275 EUR Description: Available in various conjugation types.![]()
Annexin A7
E8ER1903-73 EnoGene 100ul 275 EUR Description: Available in various conjugation types.![]()
Annexin V
E8ET1702-62 EnoGene 100ul 275 EUR Description: Available in various conjugation types.![]()
Annexin A2
E8ET1704-49 EnoGene 100ul 275 EUR Description: Available in various conjugation types.![]()
Annexin IV
E8ET7108-56 EnoGene 100ul 275 EUR Description: Available in various conjugation types.![]()
Annexin A10
PR27208 Neuromics 5 ug 229.2 EUR ![]()
Annexin A11
PR27209 Neuromics 5 ug 229.2 EUR ![]()
Annexin A13
PR27210 Neuromics 2 ug 229.2 EUR ![]()
Annexin A13
E8ER1903-72 EnoGene 100ul 275 EUR Description: Available in various conjugation types.![]()
Annexin A10
E8ET1610-57 EnoGene 100ul 275 EUR Description: Available in various conjugation types.![]()
Annexin Peptide
45-007P ProSci 0.1 mg 405.6 EUR Description: (NT) Annexin A11 Peptide![]()
Annexin Peptide
45-008P ProSci 0.1 mg 405.6 EUR Description: (NT) Annexin A2 Peptide![]()
Recombinant human Annexin A5/Annexin V/ANXA5 Protein
RP01180 Abclonal 10 μg 186 EUR ![]()
Annexin V (PE)
abx090613-100tests Abbexa 100 tests 644.4 EUR ![]()
Annexin V PE
EXB0027 ExBio 100 tests 244.8 EUR ![]()
Annexin V (APC)
abx090615-100tests Abbexa 100 tests 718.8 EUR ![]()
Annexin V APC
EXB0028 ExBio 100 tests 244.8 EUR ![]()
Annexin-2 Antibody
39396-100ul SAB 100ul 468 EUR ![]()
Annexin-2 Antibody
E312231 EnoGene 200ul 275 EUR Description: Available in various conjugation types.![]()
Annexin-2 Antibody
E300092 EnoGene 100ug/200ul 275 EUR Description: Available in various conjugation types.![]()
Polyclonal ANXA6/Annexin A6/Annexin VI Antibody (aa1-50)
APR02865G Leading Biology 0.05ml 580.8 EUR Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ANXA6/Annexin A6/Annexin VI (aa1-50). This antibody is tested and proven to work in the following applications:![]()
Annexin V (FITC)
abx090611-100tests Abbexa 100 tests 510 EUR ![]()
Annexin V FITC
EXB0024 ExBio 100 tests 244.8 EUR ![]()
Annexin V- FITC
E16FXP018a-100T EnoGene 100 tests 400 EUR Description: Available in various conjugation types.![]()
Annexin V, CF770
29046 Biotium 25ug 410.4 EUR Description: Minimum order quantity: 1 unit of 25ug![]()
Annexin V, CF790
29047 Biotium 25ug 439.2 EUR Description: Minimum order quantity: 1 unit of 25ug![]()
Annexin A3 siRNA
20-abx907669 Abbexa
- 661.20 EUR
- 878.40 EUR
- 15 nmol
- 30 nmol
![]()
Annexin A3 siRNA
20-abx907670 Abbexa
- 661.20 EUR
- 878.40 EUR
- 15 nmol
- 30 nmol
![]()
Annexin V siRNA
20-abx907673 Abbexa
- 661.20 EUR
- 878.40 EUR
- 15 nmol
- 30 nmol
![]()
Annexin V siRNA
20-abx907674 Abbexa
- 661.20 EUR
- 878.40 EUR
- 15 nmol
- 30 nmol
![]()
Annexin A3 siRNA
20-abx900342 Abbexa
- 661.20 EUR
- 878.40 EUR
- 15 nmol
- 30 nmol
![]()
Annexin V siRNA
20-abx900343 Abbexa
- 661.20 EUR
- 878.40 EUR
- 15 nmol
- 30 nmol
![]()
ANXA1 (Annexin A1)
MO47023 Neuromics 100 ul 418.8 EUR ![]()
Annexin A2/ANXA2
E21-205 EnoGene 10ug 411.6 EUR ![]()
Annexin V, Human
E34M143H EnoGene 5 μg 155 EUR ![]()
Annexin V, sulforhodamine 101 conjugate (Texas-Red Annexin V)
29002 Biotium 0.5ML 332.4 EUR Description: Minimum order quantity: 1 unit of 0.5ML![]()
Annexin A5 Protein
20-abx260555 Abbexa
- 3433.20 EUR
- 393.60 EUR
- 276.00 EUR
- 1 mg
- 20 ug
- 5 ug
![]()
Annexin A3 Protein
20-abx260563 Abbexa
- 3433.20 EUR
- 393.60 EUR
- 276.00 EUR
- 1 mg
- 20 ug
- 5 ug
![]()
Annexin A7 Protein
20-abx261405 Abbexa
- 4101.60 EUR
- 393.60 EUR
- 276.00 EUR
- 1 mg
- 20 ug
- 5 ug
![]()
Annexin A8 Protein
20-abx261421 Abbexa
- 4101.60 EUR
- 393.60 EUR
- 276.00 EUR
- 1 mg
- 20 ug
- 5 ug
![]()
Annexin A4 Protein
20-abx262872 Abbexa
- 393.60 EUR
- 7676.40 EUR
- 276.00 EUR
- 10 ug
- 1 mg
- 2 µg
![]()
Annexin A6 Protein
20-abx262873 Abbexa
- 393.60 EUR
- 7676.40 EUR
- 276.00 EUR
- 10 ug
- 1 mg
- 2 µg
![]()
Annexin A1 protein
30R-1291 Fitzgerald 20 ug 548.4 EUR Description: Purified recombinant Human Annexin A1 protein![]()
Annexin A5 protein
30R-1406 Fitzgerald 100 ug 321.6 EUR Description: Purified recombinant Human Annexin A5 protein![]()
Annexin A3 protein
30R-1453 Fitzgerald 100 ug 321.6 EUR Description: Purified recombinant Human Annexin A3 protein![]()
Annexin A4 protein
30R-1463 Fitzgerald 100 ug 703.2 EUR Description: Purified recombinant Human Annexin A4 protein![]()
Annexin A5 protein
30R-3209 Fitzgerald 50 ug 308.4 EUR Description: Purified recombinant Annexin A5 protein![]()
Annexin A3 Protein
abx061599-200ug Abbexa 200 ug 1528.8 EUR ![]()
Annexin A1 Peptide
46-785P ProSci 0.1 mg 405.6 EUR Description: ANXA1 Peptide![]()
Recombinant human Annexin A5/Annexin V/ANXA5 Protein, His Tag
E40KMP1303 EnoGene 20ug 495 EUR ![]()
Annexin A13 Protein
20-abx261320 Abbexa
- 4101.60 EUR
- 393.60 EUR
- 276.00 EUR
- 1 mg
- 20 ug
- 5 ug
![]()
Annexin I antibody
10-2468 Fitzgerald 250 ug 590.4 EUR Description: Mouse monoclonal Annexin I antibody![]()
Annexin I antibody
10-2469 Fitzgerald 250 ug 590.4 EUR Description: Mouse monoclonal Annexin I antibody![]()
Annexin 1 antibody
10R-11422 Fitzgerald 100 ul 418.8 EUR Description: Mouse Monoclonal Annexin 1 antibody![]()
Annexin V antibody
10R-7939 Fitzgerald 100 ug 516 EUR Description: Mouse monoclonal Annexin V antibody![]()
Annexin VI Antibody
21672-100ul SAB 100ul 302.4 EUR ![]()
Annexin VI Antibody
21672-50ul SAB 50ul 224.4 EUR ![]()
Annexin A1 antibody
22818-100ul SAB 100ul 468 EUR ![]()
Annexin V antibody
20R-1522 Fitzgerald 100 ug 781.2 EUR Description: Rabbit polyclonal Annexin V antibody![]()
Annexin A5 Antibody
39410-100ul SAB 100ul 468 EUR ![]()
Annexin A2 Antibody
39291-100ul SAB 100ul 468 EUR ![]()
Annexin A10 Peptide
45-255P ProSci 0.1 mg 405.6 EUR Description: Annexin A10 / Annexin 14 Peptide![]()
Annexin A6 antibody
70R-31098 Fitzgerald 100 ug 392.4 EUR Description: Rabbit polyclonal Annexin A6 antibody![]()
Annexin A2 Antibody
AF5420 Affbiotech 200ul 420 EUR ![]()
Annexin V antibody
70R-11770 Fitzgerald 100 ug 632.4 EUR Description: Rabbit polyclonal Annexin V antibody![]()
Annexin V Antibody
49376-100ul SAB 100ul 399.6 EUR ![]()
Annexin V Antibody
49376-50ul SAB 50ul 286.8 EUR ![]()
Annexin A2 Antibody
49559-100ul SAB 100ul 399.6 EUR ![]()
Annexin A2 Antibody
49559-50ul SAB 50ul 286.8 EUR ![]()
Annexin A7 antibody
70R-1680 Fitzgerald 100 ug 452.4 EUR Description: Rabbit polyclonal Annexin A7 antibody raised against the N terminal of ANXA7![]()
Annexin A1 antibody
70R-1703 Fitzgerald 100 ug 452.4 EUR Description: Rabbit polyclonal Annexin A1 antibody raised against the N terminal of ANXA1![]()
Annexin A1 antibody
70R-13525 Fitzgerald 100 ul 548.4 EUR Description: Affinity purified Rabbit polyclonal Annexin A1 antibody![]()
Annexin I antibody
70R-13689 Fitzgerald 100 ug 386.4 EUR Description: Affinity purified Rabbit polyclonal Annexin I antibody![]()
Annexin IV antibody
70R-13690 Fitzgerald 100 ug 386.4 EUR Description: Affinity purified Rabbit polyclonal Annexin IV antibody![]()
Annexin V antibody
70R-13691 Fitzgerald 100 ug 386.4 EUR Description: Affinity purified Rabbit polyclonal Annexin V antibody![]()
Annexin A2 antibody
70R-13890 Fitzgerald 100 ug 386.4 EUR Description: Affinity purified Rabbit polyclonal Annexin A2 antibody![]()
Annexin A6 antibody
70R-13975 Fitzgerald 100 ug 386.4 EUR Description: Affinity purified Rabbit polyclonal Annexin A6 antibody![]()
Annexin A8 antibody
70R-14039 Fitzgerald 100 ug 418.8 EUR Description: Affinity purified Rabbit polyclonal Annexin A8 antibody![]()
Annexin A3 antibody
70R-14049 Fitzgerald 100 ug 386.4 EUR Description: Affinity purified Rabbit polyclonal Annexin A3 antibody![]()
Annexin A2 antibody
70R-15166 Fitzgerald 100 ug 392.4 EUR Description: Rabbit polyclonal Annexin A2 antibody![]()
Annexin A5 antibody
70R-15224 Fitzgerald 100 ug 392.4 EUR Description: Rabbit polyclonal Annexin A5 antibody![]()
Annexin A7 antibody
70R-1667 Fitzgerald 100 ug 452.4 EUR Description: Rabbit polyclonal Annexin A7 antibody raised against the N terminal of ANXA7![]()
Annexin A5 antibody
70R-1668 Fitzgerald 100 ug 452.4 EUR Description: Rabbit polyclonal Annexin A5 antibody raised against the N terminal of ANXA5![]()
Annexin A5 antibody
70R-1669 Fitzgerald 100 ug 452.4 EUR Description: Rabbit polyclonal Annexin A5 antibody raised against the N terminal of ANXA5![]()
Annexin A6 antibody
70R-1672 Fitzgerald 100 ug 452.4 EUR Description: Rabbit polyclonal Annexin A6 antibody raised against the C terminal of ANXA6![]()
Annexin A6 antibody
70R-1673 Fitzgerald 100 ug 452.4 EUR Description: Rabbit polyclonal Annexin A6 antibody raised against the N terminal of ANXA6![]()
Annexin A4 antibody
70R-1676 Fitzgerald 100 ug 452.4 EUR Description: Rabbit polyclonal Annexin A4 antibody raised against the N terminal of ANXA4![]()
Annexin A3 antibody
70R-1677 Fitzgerald 100 ug 452.4 EUR Description: Rabbit polyclonal Annexin A3 antibody raised against the N terminal of ANXA3![]()
Annexin A3 antibody
70R-1678 Fitzgerald 100 ug 452.4 EUR Description: Rabbit polyclonal Annexin A3 antibody raised against the C terminal of ANXA3![]()
Annexin A2 antibody
70R-1679 Fitzgerald 100 ug 452.4 EUR Description: Rabbit polyclonal Annexin A2 antibody raised against the C terminal of ANXA2![]()
Annexin A4 antibody
70R-6041 Fitzgerald 50 ug 560.4 EUR Description: Rabbit polyclonal Annexin A4 antibody raised against the middle region of ANXA4![]()
Annexin A2 antibody
70R-51447 Fitzgerald 100 ul 344.4 EUR Description: Purified Polyclonal Annexin A2 antibody![]()
Annexin A1 antibody
70R-49368 Fitzgerald 100 ul 292.8 EUR Description: Purified Polyclonal Annexin A1 antibody![]()
Annexin A2 antibody
70R-49369 Fitzgerald 100 ul 292.8 EUR Description: Purified Polyclonal Annexin A2 antibody![]()
Annexin A3 antibody
70R-49370 Fitzgerald 100 ul 292.8 EUR Description: Purified Polyclonal Annexin A3 antibody![]()
Annexin A6 antibody
70R-49371 Fitzgerald 100 ul 292.8 EUR Description: Purified Polyclonal Annexin A6 antibody![]()
Annexin V Antibody
3357-100 Biovision each 464.4 EUR ![]()
Annexin V Antibody
3357-30T Biovision each 175.2 EUR ![]()
Annexin XI Antibody
35334-100ul SAB 100ul 468 EUR ![]()
Annexin A6 Antibody
33322-100ul SAB 100ul 302.4 EUR ![]()
Annexin A6 Antibody
33322-50ul SAB 50ul 224.4 EUR ![]()
Annexin A3 Antibody
48531-100ul SAB 100ul 399.6 EUR ![]()
Annexin A3 Antibody
48531-50ul SAB 50ul 286.8 EUR ![]()
Annexin IV Antibody
49926-100ul SAB 100ul 399.6 EUR ![]()
Annexin IV Antibody
49926-50ul SAB 50ul 286.8 EUR ![]()
Annexin A6 Antibody
ABF0116 Lifescience Market 100 ug 525.6 EUR ![]()
Annexin?I Antibody
ABF5154 Lifescience Market 100 ug 525.6 EUR ![]()
Annexin II Antibody
ABF5171 Lifescience Market 100 ug 525.6 EUR ![]()
Annexin A5 Antibody
1-CSB-PA001846HA01EQC Cusabio
- 380.40 EUR
- 402.00 EUR
- 100ug
- 50ug
Description: A polyclonal antibody against Annexin A5. Recognizes Annexin A5 from Cynops pyrrhogaster. This antibody is Unconjugated. Tested in the following application: ELISA![]()
Annexin V Antibody
F49706-0.08ML NSJ Bioreagents 0.08 ml 140.25 EUR Description: Annexin 5 belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII.![]()
Annexin V Antibody
F49706-0.4ML NSJ Bioreagents 0.4 ml 322.15 EUR Description: Annexin 5 belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII.![]()
Annexin V Antibody
F49707-0.08ML NSJ Bioreagents 0.08 ml 140.25 EUR Description: Annexin 5 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. [UniProt]![]()
Annexin V Antibody
F49707-0.4ML NSJ Bioreagents 0.4 ml 322.15 EUR Description: Annexin 5 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. [UniProt]![]()
Annexin A1 Antibody
F49712-0.08ML NSJ Bioreagents 0.08 ml 140.25 EUR Description: Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.![]()
Annexin A1 Antibody
F49712-0.4ML NSJ Bioreagents 0.4 ml 322.15 EUR Description: Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.![]()
Annexin V antibody
PAab09988 Lifescience Market 100 ug 463.2 EUR ![]()
Annexin A1 Antibody
P1024-01m SAB 0.1m 242.4 EUR ![]()
Annexin A1 Antibody
P1024-1ml SAB 1ml 529.2 EUR ![]()
Annexin A1 Antibody
R30173 NSJ Bioreagents 100 ug 356.15 EUR Description: Annexin I, also known as lipocortin I(Lipo1), belongs to the family of annexins. These proteins are though to control the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes. In two lipocortins(I and II) a short amino-terminal sequence distinct from the core structure has potential regulatory functions which are dependent on its phosphorylation state. The gene in the mouse encodes a protein of 346 amino acid residues. Mouse Lipo1 gene spans about 17 kb and is divided into 13 exons. Annexin I gene, mapped to 9q11-q22, is located on mouse chromosome 19. Annexin I acts through the formyl peptide receptor on human neutrophils. Peptides derived from the unique N-terminal domain of annexin I serve as FPR ligands and trigger different signaling pathways in a dose-dependent manner.![]()
Annexin V Antibody
R30176 NSJ Bioreagents 100 ug 356.15 EUR Description: Annexin V is also know as endonnexin II (ENX2),or placental protein 4 (PP4). It is a member of the family of Ca(2+)-dependent phospholipid binding proteins, known as annexins. It bind to the phospholipids that are preferentially located on the cytosolic face of the plasma membrane. Annexin V has a relative molecular weight of about 35,000. The gene lies on mouse chromosome 3 in close linkage with the fibroblast growth factor 2(basic) gene and is syntenic with other genes known to have orthologous counterparts on human chromosome 4q. The cDNA encoded a protein of 320 amino acid residues. A single mRNA, approximately 1.6 kb long, was found to be expressed in human cell lines and placenta. It is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.![]()
Annexin A2 Antibody
R30414 NSJ Bioreagents 100 ug 356.15 EUR Description: Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene. The ANXA2 gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. This protein is a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. Richard et al.(1994) presented an integration of the physical, expression, and genetic maps of human chromosome 15. They placed the ANXA2 gene in their region IV, i.e., 15q21-q22, thus confirming the previous localization.![]()
Annexin VI Antibody
R30506 NSJ Bioreagents 100 ug 356.15 EUR Description: Annexin VI (ANXA6) is a member of a family of proteins that bind membrane or cytoskeleton in a Ca(2+)-dependent manner. These proteins are characterized by homologous amino acid sequences that are present in multiple copies in each protein. ANXA6 gene is assigned to 5q32-q34 by use of a cDNA clone to probe genomic DNA from rodent-human somatic cell hybrids and for in situ hybridization.The ANX6 gene is approximately 60 kb long and contains 26 exons. The genomic sequence at the 3-prime end does not contain a canonical polyadenylylation signal.Ca(2+)-dependent binding between CRHSP28 and ANXA6 is required for acinar cell membrane trafficking events and digestive enzyme secretion![]()
Annexin A3 Antibody
R30583 NSJ Bioreagents 100 ug 356.15 EUR Description: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The gene contains 13 exons and spans 58 kb of genomic DNA and is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.![]()
Annexin V Antibody
R31475 NSJ Bioreagents 100 ug 356.15 EUR Description: Annexin V or A5 has been proposed to play a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with prothrombin and also to inhibit the activity of phospholipase A1. This protein is an anticoagulant protein, it can form a shield around negatively-charged phospholipid molecules, the formation of an Annexin V shield blocks the entry of phospholipids into coagulation (clotting) reactions. Annexin AV can also act as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.![]()
Annexin A1 Antibody
R31548 NSJ Bioreagents 100 ug 356.15 EUR Description: ANXA1, also known as Lipocortin I or Annexin A1, is a protein that in humans is encoded by the ANXA1 gene. It is mapped to 9q21.13. It belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. ANXA1 protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Lower peptide concentrations possibly found in inflammatory situations elicit Ca(2+) transients without fully activating the mitogen-activated protein kinase pathway. This causes a specific inhibition of the transendothelial migration of neutrophils and a desensitization of neutrophils toward a chemoattractant challenge. These findings identified ANXA1 peptides as novel, endogenous FPR ligands and established a mechanistic basis of ANXA1-mediated antiinflammatory effects.![]()
Annexin A3 Antibody
R31948 NSJ Bioreagents 100 ug 356.15 EUR Description: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.![]()
Annexin IV Antibody
R32677 NSJ Bioreagents 100ug 356.15 EUR Description: ANXA4 (Annexin A4), also known as ANX4, is a protein that in humans is encoded by the ANXA4 gene. It belongs to the annexin family of calcium-dependent phospholipid binding proteins. By PCR analysis of somatic cell hybrids and in situ hybridization with a cDNA probe, the human ANXA4 gene is mapped to chromosome 2p13. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. And ANXA4 is almost exclusively expressed in epithelial cells.![]()
Annexin A1 Antibody
R33307-100UG NSJ Bioreagents 100 ug 339.15 EUR Description: Additional name(s) for this target protein: ANXA1![]()
Annexin A1 Antibody
V3736-100UG NSJ Bioreagents 100 ug 349.3 EUR Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.![]()
Annexin A1 Antibody
V3736-20UG NSJ Bioreagents 20 ug 153.3 EUR Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.![]()
Annexin A1 Antibody
V3736SAF-100UG NSJ Bioreagents 100 ug 349.3 EUR Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.![]()
Annexin A1 Antibody
V3741-100UG NSJ Bioreagents 100 ug 349.3 EUR Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.![]()
Annexin A1 Antibody
V3741-20UG NSJ Bioreagents 20 ug 153.3 EUR Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.![]()
Annexin A1 Antibody
V3741IHC-7ML NSJ Bioreagents 7 ml 349.3 EUR Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.![]()
Annexin A1 Antibody
V3741SAF-100UG NSJ Bioreagents 100 ug 349.3 EUR Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.![]()
Annexin A1 Antibody
V7283-100UG NSJ Bioreagents 100 ug 349.3 EUR Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.![]()
Annexin A1 Antibody
V7283-20UG NSJ Bioreagents 20 ug 153.3 EUR Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.![]()
Annexin A1 Antibody
V7283IHC-7ML NSJ Bioreagents 7 ml 349.3 EUR Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.![]()
Annexin A1 Antibody
V7283SAF-100UG NSJ Bioreagents 100 ug 349.3 EUR Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.![]()
Annexin V Antibody
RQ5261 NSJ Bioreagents 100ul 356.15 EUR Description: The protein encoded by the ANXA5 gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. [RefSeq]![]()
Annexin VI Antibody
RQ6590 NSJ Bioreagents 100ug 356.15 EUR Description: Annexin A6 (ANXA6) is a member of a family of proteins that bind membrane or cytoskeleton in a Ca(2+)-dependent manner. These proteins are characterized by homologous amino acid sequences that are present in multiple copies in each protein. ANXA6 gene is assigned to 5q32-q34 by use of a cDNA clone to probe genomic DNA from rodent-human somatic cell hybrids and for in situ hybridization. The ANX6 gene is approximately 60 kb long and contains 26 exons. The genomic sequence at the 3-prime end does not contain a canonical polyadenylylation signal. Ca(2+)-dependent binding between CRHSP28 and ANXA6 is required for acinar cell membrane trafficking events and digestive enzyme secretion.![]()
Annexin VI Antibody
RQ4425 NSJ Bioreagents 100 ug 356.15 EUR Description: Annexin A6 (ANXA6) is a member of a family of proteins that bind membrane or cytoskeleton in a Ca(2+)-dependent manner. These proteins are characterized by homologous amino acid sequences that are present in multiple copies in each protein. ANXA6 gene is assigned to 5q32-q34 by use of a cDNA clone to probe genomic DNA from rodent-human somatic cell hybrids and for in situ hybridization. The ANX6 gene is approximately 60 kb long and contains 26 exons. The genomic sequence at the 3-prime end does not contain a canonical polyadenylylation signal. Ca(2+)-dependent binding between CRHSP28 and ANXA6 is required for acinar cell membrane trafficking events and digestive enzyme secretion.![]()
Annexin A3 Antibody
RQ4892 NSJ Bioreagents 100ug 356.15 EUR Description: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.![]()
Annexin A6 Antibody
AF0116-100ul Affinity Biosciences 100ul 280 EUR ![]()
Annexin A6 Antibody
AF0116-200ul Affinity Biosciences 200ul 350 EUR ![]()
Annexin A7 Antibody
E38PA3769 EnoGene 100ul 225 EUR Description: Available in various conjugation types.![]()
Annexin A1 Antibody
E38PA4563 EnoGene 100ul 225 EUR Description: Available in various conjugation types.![]()
Annexin A1 Antibody
DF6254 Affinity Biosciences 100ul 280 EUR Description: Human,Mouse,Rat![]()
Annexin A2 Antibody
DF6468 Affinity Biosciences 100ul 280 EUR Description: Human,Mouse,Rat![]()
Annexin V Antibody
DF6580 Affinity Biosciences 100ul 280 EUR Description: Human,Mouse,Rat![]()
Annexin IV Antibody
DF8068 Affinity Biosciences 100ul 280 EUR Description: Human,Mouse![]()
Annexin A1 Antibody
AF5154-100ul Affinity Biosciences 100ul 280 EUR ![]()
Annexin A1 Antibody
AF5154-200ul Affinity Biosciences 200ul 350 EUR ![]()
Annexin A2 Antibody
AF5171-100ul Affinity Biosciences 100ul 280 EUR ![]()
Annexin A2 Antibody
AF5171-200ul Affinity Biosciences 200ul 350 EUR ![]()
Annexin A1 Antibody
AF5328-100ul Affinity Biosciences 100ul 280 EUR ![]()
Annexin A1 Antibody
AF5328-200ul Affinity Biosciences 200ul 350 EUR ![]()
Annexin A1 Antibody
DF6254-100ul Affinity Biosciences 100ul 280 EUR
Collectively, these data suggest that MEHP induces oxidative stress by disrupting the activities of antioxidant enzymes. This may lead to decreased expression of cell-cycle regulators and antiapoptotic regulators and increased expression of proapoptotic factors, which then may lead to inhibition of follicle growth.