Mono-(2-ethylhexyl) phthalate induces oxidative stress and inhibits growth of mouse ovarian antral follicles.

Mono-(2-ethylhexyl) phthalate (MEHP) is the active metabolite of the most commonly used plasticizer, di-(2-ethylhexyl) phthalate, and is considered to be a reproductive toxicant. However, little is known about the effects of MEHP on ovarian antral follicles.

Thus, the present study tested the hypothesis that MEHP inhibits follicle growth via oxidative stress pathways. The data indicate that MEHP increases reactive oxygen species (ROS) levels and inhibits follicle growth in antral follicles, whereas N-acetylcysteine (NAC; an antioxidant) restores ROS levels to control levels and rescues follicles from MEHP-induced inhibition of follicle growth.

To further analyze the mechanism by which MEHP induces oxidative stress and inhibits follicle growth, the expression and activities of various key antioxidant enzymes (copper/zinc superoxide dismutase [SOD1], glutathione peroxidase [GPX], and catalase [CAT]) and the expression of key cell-cycle regulators (Ccnd2, Ccne1, and Cdk4) and apoptotic regulators (Bcl-2 and Bax) were compared in control and MEHP-treated follicles.

The data indicate that MEHP inhibits the expression and activities of SOD1 and GPX; does not inhibit Cat expression; inhibits the expression of Ccnd2, Ccne1, Cdk4, and Bcl-2; but increases the expression of Bax compared to controls. Furthermore, NAC blocks these toxic effects of MEHP.

Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-10ug

QP8982-ye-10ug EnQuireBio 10ug 369.6 EUR

Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-50ug

QP8982-ye-50ug EnQuireBio 50ug 500.4 EUR

Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-100ug

QP8982-ye-100ug EnQuireBio 100ug 804 EUR

Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-200ug

QP8982-ye-200ug EnQuireBio 200ug 1282.8 EUR

Recombinant Human ANXA5/ Annexin 5/ Annexin A5 Protein, His, Yeast-500ug

QP8982-ye-500ug EnQuireBio 500ug 2164.8 EUR

Annexin VII (Annexin VII) Antibody

abx230439-100ug Abbexa 100 ug 610.8 EUR

Horse ANX5(Annexin 5) ELISA Kit

EHS0047 FN Test 96T 681.12 EUR
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Horse;Sensitivity: 0.938 ng/ml

Annexin VIII (Annexin VIII) Antibody

abx230440-100ug Abbexa 100 ug 577.2 EUR

Annexin VI/Annexin A6 Rabbit pAb

E2382616 EnoGene 100ul 225 EUR
Description: Available in various conjugation types.

Annexin A4/Annexin IV Rabbit mAb

A9203 Abclonal 50μL 1557.4 EUR
Description: A synthetic peptide of human CD62P/P-selectin.

Annexin A5/Annexin V Rabbit mAb

A9262 Abclonal 200μL 213.2 EUR
Description: Recombinant fusion protein containing a sequence corresponding to amino acids 165-225 of human CD79a (NP_001774.1).

Annexin A6/Annexin VI Rabbit mAb

A22038 Abclonal 500μL 83.2 EUR
Description: Recombinant protein of Human PMF1.

Annexin V 647

E16FXP023a-100T EnoGene 100 tests 433.33 EUR
Description: Available in various conjugation types.

Annexin A1

PR27207 Neuromics 2 ug 465.6 EUR

Annexin A2

PR27211 Neuromics 5 ug 229.2 EUR

Annexin A3

PR27212 Neuromics 5 ug 229.2 EUR

Annexin A4

PR27213 Neuromics 2 ug 229.2 EUR

Annexin A5

PR27214 Neuromics 5 ug 229.2 EUR

Annexin A6

PR27215 Neuromics 2 ug 229.2 EUR

Annexin A7

PR27216 Neuromics 5 ug 229.2 EUR

Annexin A8

PR27217 Neuromics 5 ug 229.2 EUR

Annexin A3

E8ER1802-50 EnoGene 100ul 275 EUR
Description: Available in various conjugation types.

Annexin A1

E8ER1803-70 EnoGene 100ul 275 EUR
Description: Available in various conjugation types.

Annexin A7

E8ER1903-73 EnoGene 100ul 275 EUR
Description: Available in various conjugation types.

Annexin V

E8ET1702-62 EnoGene 100ul 275 EUR
Description: Available in various conjugation types.

Annexin A2

E8ET1704-49 EnoGene 100ul 275 EUR
Description: Available in various conjugation types.

Annexin IV

E8ET7108-56 EnoGene 100ul 275 EUR
Description: Available in various conjugation types.

Annexin A10

PR27208 Neuromics 5 ug 229.2 EUR

Annexin A11

PR27209 Neuromics 5 ug 229.2 EUR

Annexin A13

PR27210 Neuromics 2 ug 229.2 EUR

Annexin A13

E8ER1903-72 EnoGene 100ul 275 EUR
Description: Available in various conjugation types.

Annexin A10

E8ET1610-57 EnoGene 100ul 275 EUR
Description: Available in various conjugation types.

Annexin Peptide

45-007P ProSci 0.1 mg 405.6 EUR
Description: (NT) Annexin A11 Peptide

Annexin Peptide

45-008P ProSci 0.1 mg 405.6 EUR
Description: (NT) Annexin A2 Peptide

Recombinant human Annexin A5/Annexin V/ANXA5 Protein

RP01180 Abclonal 10 μg 186 EUR

Annexin V (PE)

abx090613-100tests Abbexa 100 tests 644.4 EUR

Annexin V PE

EXB0027 ExBio 100 tests 244.8 EUR

Annexin V (APC)

abx090615-100tests Abbexa 100 tests 718.8 EUR

Annexin V APC

EXB0028 ExBio 100 tests 244.8 EUR

Annexin-2 Antibody

39396-100ul SAB 100ul 468 EUR

Annexin-2 Antibody

E312231 EnoGene 200ul 275 EUR
Description: Available in various conjugation types.

Annexin-2 Antibody

E300092 EnoGene 100ug/200ul 275 EUR
Description: Available in various conjugation types.

Polyclonal ANXA6/Annexin A6/Annexin VI Antibody (aa1-50)

APR02865G Leading Biology 0.05ml 580.8 EUR
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ANXA6/Annexin A6/Annexin VI (aa1-50). This antibody is tested and proven to work in the following applications:

Annexin V (FITC)

abx090611-100tests Abbexa 100 tests 510 EUR

Annexin V FITC

EXB0024 ExBio 100 tests 244.8 EUR

Annexin V- FITC

E16FXP018a-100T EnoGene 100 tests 400 EUR
Description: Available in various conjugation types.

Annexin V, CF770

29046 Biotium 25ug 410.4 EUR
Description: Minimum order quantity: 1 unit of 25ug

Annexin V, CF790

29047 Biotium 25ug 439.2 EUR
Description: Minimum order quantity: 1 unit of 25ug

Annexin A3 siRNA

20-abx907669 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

Annexin A3 siRNA

20-abx907670 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

Annexin V siRNA

20-abx907673 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

Annexin V siRNA

20-abx907674 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

Annexin A3 siRNA

20-abx900342 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

Annexin V siRNA

20-abx900343 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

ANXA1 (Annexin A1)

MO47023 Neuromics 100 ul 418.8 EUR

Annexin A2/ANXA2

E21-205 EnoGene 10ug 411.6 EUR

Annexin V, Human

E34M143H EnoGene 5 μg 155 EUR

Annexin V, sulforhodamine 101 conjugate (Texas-Red Annexin V)

29002 Biotium 0.5ML 332.4 EUR
Description: Minimum order quantity: 1 unit of 0.5ML

Annexin A5 Protein

20-abx260555 Abbexa
  • 3433.20 EUR
  • 393.60 EUR
  • 276.00 EUR
  • 1 mg
  • 20 ug
  • 5 ug

Annexin A3 Protein

20-abx260563 Abbexa
  • 3433.20 EUR
  • 393.60 EUR
  • 276.00 EUR
  • 1 mg
  • 20 ug
  • 5 ug

Annexin A7 Protein

20-abx261405 Abbexa
  • 4101.60 EUR
  • 393.60 EUR
  • 276.00 EUR
  • 1 mg
  • 20 ug
  • 5 ug

Annexin A8 Protein

20-abx261421 Abbexa
  • 4101.60 EUR
  • 393.60 EUR
  • 276.00 EUR
  • 1 mg
  • 20 ug
  • 5 ug

Annexin A4 Protein

20-abx262872 Abbexa
  • 393.60 EUR
  • 7676.40 EUR
  • 276.00 EUR
  • 10 ug
  • 1 mg
  • 2 µg

Annexin A6 Protein

20-abx262873 Abbexa
  • 393.60 EUR
  • 7676.40 EUR
  • 276.00 EUR
  • 10 ug
  • 1 mg
  • 2 µg

Annexin A1 protein

30R-1291 Fitzgerald 20 ug 548.4 EUR
Description: Purified recombinant Human Annexin A1 protein

Annexin A5 protein

30R-1406 Fitzgerald 100 ug 321.6 EUR
Description: Purified recombinant Human Annexin A5 protein

Annexin A3 protein

30R-1453 Fitzgerald 100 ug 321.6 EUR
Description: Purified recombinant Human Annexin A3 protein

Annexin A4 protein

30R-1463 Fitzgerald 100 ug 703.2 EUR
Description: Purified recombinant Human Annexin A4 protein

Annexin A5 protein

30R-3209 Fitzgerald 50 ug 308.4 EUR
Description: Purified recombinant Annexin A5 protein

Annexin A3 Protein

abx061599-200ug Abbexa 200 ug 1528.8 EUR

Annexin A1 Peptide

46-785P ProSci 0.1 mg 405.6 EUR
Description: ANXA1 Peptide

Recombinant human Annexin A5/Annexin V/ANXA5 Protein, His Tag

E40KMP1303 EnoGene 20ug 495 EUR

Annexin A13 Protein

20-abx261320 Abbexa
  • 4101.60 EUR
  • 393.60 EUR
  • 276.00 EUR
  • 1 mg
  • 20 ug
  • 5 ug

Annexin I antibody

10-2468 Fitzgerald 250 ug 590.4 EUR
Description: Mouse monoclonal Annexin I antibody

Annexin I antibody

10-2469 Fitzgerald 250 ug 590.4 EUR
Description: Mouse monoclonal Annexin I antibody

Annexin 1 antibody

10R-11422 Fitzgerald 100 ul 418.8 EUR
Description: Mouse Monoclonal Annexin 1 antibody

Annexin V antibody

10R-7939 Fitzgerald 100 ug 516 EUR
Description: Mouse monoclonal Annexin V antibody

Annexin VI Antibody

21672-100ul SAB 100ul 302.4 EUR

Annexin VI Antibody

21672-50ul SAB 50ul 224.4 EUR

Annexin A1 antibody

22818-100ul SAB 100ul 468 EUR

Annexin V antibody

20R-1522 Fitzgerald 100 ug 781.2 EUR
Description: Rabbit polyclonal Annexin V antibody

Annexin A5 Antibody

39410-100ul SAB 100ul 468 EUR

Annexin A2 Antibody

39291-100ul SAB 100ul 468 EUR

Annexin A10 Peptide

45-255P ProSci 0.1 mg 405.6 EUR
Description: Annexin A10 / Annexin 14 Peptide

Annexin A6 antibody

70R-31098 Fitzgerald 100 ug 392.4 EUR
Description: Rabbit polyclonal Annexin A6 antibody

Annexin A2 Antibody

AF5420 Affbiotech 200ul 420 EUR

Annexin V antibody

70R-11770 Fitzgerald 100 ug 632.4 EUR
Description: Rabbit polyclonal Annexin V antibody

Annexin V Antibody

49376-100ul SAB 100ul 399.6 EUR

Annexin V Antibody

49376-50ul SAB 50ul 286.8 EUR

Annexin A2 Antibody

49559-100ul SAB 100ul 399.6 EUR

Annexin A2 Antibody

49559-50ul SAB 50ul 286.8 EUR

Annexin A7 antibody

70R-1680 Fitzgerald 100 ug 452.4 EUR
Description: Rabbit polyclonal Annexin A7 antibody raised against the N terminal of ANXA7

Annexin A1 antibody

70R-1703 Fitzgerald 100 ug 452.4 EUR
Description: Rabbit polyclonal Annexin A1 antibody raised against the N terminal of ANXA1

Annexin A1 antibody

70R-13525 Fitzgerald 100 ul 548.4 EUR
Description: Affinity purified Rabbit polyclonal Annexin A1 antibody

Annexin I antibody

70R-13689 Fitzgerald 100 ug 386.4 EUR
Description: Affinity purified Rabbit polyclonal Annexin I antibody

Annexin IV antibody

70R-13690 Fitzgerald 100 ug 386.4 EUR
Description: Affinity purified Rabbit polyclonal Annexin IV antibody

Annexin V antibody

70R-13691 Fitzgerald 100 ug 386.4 EUR
Description: Affinity purified Rabbit polyclonal Annexin V antibody

Annexin A2 antibody

70R-13890 Fitzgerald 100 ug 386.4 EUR
Description: Affinity purified Rabbit polyclonal Annexin A2 antibody

Annexin A6 antibody

70R-13975 Fitzgerald 100 ug 386.4 EUR
Description: Affinity purified Rabbit polyclonal Annexin A6 antibody

Annexin A8 antibody

70R-14039 Fitzgerald 100 ug 418.8 EUR
Description: Affinity purified Rabbit polyclonal Annexin A8 antibody

Annexin A3 antibody

70R-14049 Fitzgerald 100 ug 386.4 EUR
Description: Affinity purified Rabbit polyclonal Annexin A3 antibody

Annexin A2 antibody

70R-15166 Fitzgerald 100 ug 392.4 EUR
Description: Rabbit polyclonal Annexin A2 antibody

Annexin A5 antibody

70R-15224 Fitzgerald 100 ug 392.4 EUR
Description: Rabbit polyclonal Annexin A5 antibody

Annexin A7 antibody

70R-1667 Fitzgerald 100 ug 452.4 EUR
Description: Rabbit polyclonal Annexin A7 antibody raised against the N terminal of ANXA7

Annexin A5 antibody

70R-1668 Fitzgerald 100 ug 452.4 EUR
Description: Rabbit polyclonal Annexin A5 antibody raised against the N terminal of ANXA5

Annexin A5 antibody

70R-1669 Fitzgerald 100 ug 452.4 EUR
Description: Rabbit polyclonal Annexin A5 antibody raised against the N terminal of ANXA5

Annexin A6 antibody

70R-1672 Fitzgerald 100 ug 452.4 EUR
Description: Rabbit polyclonal Annexin A6 antibody raised against the C terminal of ANXA6

Annexin A6 antibody

70R-1673 Fitzgerald 100 ug 452.4 EUR
Description: Rabbit polyclonal Annexin A6 antibody raised against the N terminal of ANXA6

Annexin A4 antibody

70R-1676 Fitzgerald 100 ug 452.4 EUR
Description: Rabbit polyclonal Annexin A4 antibody raised against the N terminal of ANXA4

Annexin A3 antibody

70R-1677 Fitzgerald 100 ug 452.4 EUR
Description: Rabbit polyclonal Annexin A3 antibody raised against the N terminal of ANXA3

Annexin A3 antibody

70R-1678 Fitzgerald 100 ug 452.4 EUR
Description: Rabbit polyclonal Annexin A3 antibody raised against the C terminal of ANXA3

Annexin A2 antibody

70R-1679 Fitzgerald 100 ug 452.4 EUR
Description: Rabbit polyclonal Annexin A2 antibody raised against the C terminal of ANXA2

Annexin A4 antibody

70R-6041 Fitzgerald 50 ug 560.4 EUR
Description: Rabbit polyclonal Annexin A4 antibody raised against the middle region of ANXA4

Annexin A2 antibody

70R-51447 Fitzgerald 100 ul 344.4 EUR
Description: Purified Polyclonal Annexin A2 antibody

Annexin A1 antibody

70R-49368 Fitzgerald 100 ul 292.8 EUR
Description: Purified Polyclonal Annexin A1 antibody

Annexin A2 antibody

70R-49369 Fitzgerald 100 ul 292.8 EUR
Description: Purified Polyclonal Annexin A2 antibody

Annexin A3 antibody

70R-49370 Fitzgerald 100 ul 292.8 EUR
Description: Purified Polyclonal Annexin A3 antibody

Annexin A6 antibody

70R-49371 Fitzgerald 100 ul 292.8 EUR
Description: Purified Polyclonal Annexin A6 antibody

Annexin V Antibody

3357-100 Biovision each 464.4 EUR

Annexin V Antibody

3357-30T Biovision each 175.2 EUR

Annexin XI Antibody

35334-100ul SAB 100ul 468 EUR

Annexin A6 Antibody

33322-100ul SAB 100ul 302.4 EUR

Annexin A6 Antibody

33322-50ul SAB 50ul 224.4 EUR

Annexin A3 Antibody

48531-100ul SAB 100ul 399.6 EUR

Annexin A3 Antibody

48531-50ul SAB 50ul 286.8 EUR

Annexin IV Antibody

49926-100ul SAB 100ul 399.6 EUR

Annexin IV Antibody

49926-50ul SAB 50ul 286.8 EUR

Annexin A6 Antibody

ABF0116 Lifescience Market 100 ug 525.6 EUR

Annexin?I Antibody

ABF5154 Lifescience Market 100 ug 525.6 EUR

Annexin II Antibody

ABF5171 Lifescience Market 100 ug 525.6 EUR

Annexin A5 Antibody

1-CSB-PA001846HA01EQC Cusabio
  • 380.40 EUR
  • 402.00 EUR
  • 100ug
  • 50ug
Description: A polyclonal antibody against Annexin A5. Recognizes Annexin A5 from Cynops pyrrhogaster. This antibody is Unconjugated. Tested in the following application: ELISA

Annexin V Antibody

F49706-0.08ML NSJ Bioreagents 0.08 ml 140.25 EUR
Description: Annexin 5 belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII.

Annexin V Antibody

F49706-0.4ML NSJ Bioreagents 0.4 ml 322.15 EUR
Description: Annexin 5 belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII.

Annexin V Antibody

F49707-0.08ML NSJ Bioreagents 0.08 ml 140.25 EUR
Description: Annexin 5 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. [UniProt]

Annexin V Antibody

F49707-0.4ML NSJ Bioreagents 0.4 ml 322.15 EUR
Description: Annexin 5 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. [UniProt]

Annexin A1 Antibody

F49712-0.08ML NSJ Bioreagents 0.08 ml 140.25 EUR
Description: Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

Annexin A1 Antibody

F49712-0.4ML NSJ Bioreagents 0.4 ml 322.15 EUR
Description: Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

Annexin V antibody

PAab09988 Lifescience Market 100 ug 463.2 EUR

Annexin A1 Antibody

P1024-01m SAB 0.1m 242.4 EUR

Annexin A1 Antibody

P1024-1ml SAB 1ml 529.2 EUR

Annexin A1 Antibody

R30173 NSJ Bioreagents 100 ug 356.15 EUR
Description: Annexin I, also known as lipocortin I(Lipo1), belongs to the family of annexins. These proteins are though to control the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes. In two lipocortins(I and II) a short amino-terminal sequence distinct from the core structure has potential regulatory functions which are dependent on its phosphorylation state. The gene in the mouse encodes a protein of 346 amino acid residues. Mouse Lipo1 gene spans about 17 kb and is divided into 13 exons. Annexin I gene, mapped to 9q11-q22, is located on mouse chromosome 19. Annexin I acts through the formyl peptide receptor on human neutrophils. Peptides derived from the unique N-terminal domain of annexin I serve as FPR ligands and trigger different signaling pathways in a dose-dependent manner.

Annexin V Antibody

R30176 NSJ Bioreagents 100 ug 356.15 EUR
Description: Annexin V is also know as endonnexin II (ENX2),or placental protein 4 (PP4). It is a member of the family of Ca(2+)-dependent phospholipid binding proteins, known as annexins. It bind to the phospholipids that are preferentially located on the cytosolic face of the plasma membrane. Annexin V has a relative molecular weight of about 35,000. The gene lies on mouse chromosome 3 in close linkage with the fibroblast growth factor 2(basic) gene and is syntenic with other genes known to have orthologous counterparts on human chromosome 4q. The cDNA encoded a protein of 320 amino acid residues. A single mRNA, approximately 1.6 kb long, was found to be expressed in human cell lines and placenta. It is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

Annexin A2 Antibody

R30414 NSJ Bioreagents 100 ug 356.15 EUR
Description: Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene. The ANXA2 gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. This protein is a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. Richard et al.(1994) presented an integration of the physical, expression, and genetic maps of human chromosome 15. They placed the ANXA2 gene in their region IV, i.e., 15q21-q22, thus confirming the previous localization.

Annexin VI Antibody

R30506 NSJ Bioreagents 100 ug 356.15 EUR
Description: Annexin VI (ANXA6) is a member of a family of proteins that bind membrane or cytoskeleton in a Ca(2+)-dependent manner. These proteins are characterized by homologous amino acid sequences that are present in multiple copies in each protein. ANXA6 gene is assigned to 5q32-q34 by use of a cDNA clone to probe genomic DNA from rodent-human somatic cell hybrids and for in situ hybridization.The ANX6 gene is approximately 60 kb long and contains 26 exons. The genomic sequence at the 3-prime end does not contain a canonical polyadenylylation signal.Ca(2+)-dependent binding between CRHSP28 and ANXA6 is required for acinar cell membrane trafficking events and digestive enzyme secretion

Annexin A3 Antibody

R30583 NSJ Bioreagents 100 ug 356.15 EUR
Description: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The gene contains 13 exons and spans 58 kb of genomic DNA and is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

Annexin V Antibody

R31475 NSJ Bioreagents 100 ug 356.15 EUR
Description: Annexin V or A5 has been proposed to play a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with prothrombin and also to inhibit the activity of phospholipase A1. This protein is an anticoagulant protein, it can form a shield around negatively-charged phospholipid molecules, the formation of an Annexin V shield blocks the entry of phospholipids into coagulation (clotting) reactions. Annexin AV can also act as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

Annexin A1 Antibody

R31548 NSJ Bioreagents 100 ug 356.15 EUR
Description: ANXA1, also known as Lipocortin I or Annexin A1, is a protein that in humans is encoded by the ANXA1 gene. It is mapped to 9q21.13. It belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. ANXA1 protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Lower peptide concentrations possibly found in inflammatory situations elicit Ca(2+) transients without fully activating the mitogen-activated protein kinase pathway. This causes a specific inhibition of the transendothelial migration of neutrophils and a desensitization of neutrophils toward a chemoattractant challenge. These findings identified ANXA1 peptides as novel, endogenous FPR ligands and established a mechanistic basis of ANXA1-mediated antiinflammatory effects.

Annexin A3 Antibody

R31948 NSJ Bioreagents 100 ug 356.15 EUR
Description: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

Annexin IV Antibody

R32677 NSJ Bioreagents 100ug 356.15 EUR
Description: ANXA4 (Annexin A4), also known as ANX4, is a protein that in humans is encoded by the ANXA4 gene. It belongs to the annexin family of calcium-dependent phospholipid binding proteins. By PCR analysis of somatic cell hybrids and in situ hybridization with a cDNA probe, the human ANXA4 gene is mapped to chromosome 2p13. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. And ANXA4 is almost exclusively expressed in epithelial cells.

Annexin A1 Antibody

R33307-100UG NSJ Bioreagents 100 ug 339.15 EUR
Description: Additional name(s) for this target protein: ANXA1

Annexin A1 Antibody

V3736-100UG NSJ Bioreagents 100 ug 349.3 EUR
Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Annexin A1 Antibody

V3736-20UG NSJ Bioreagents 20 ug 153.3 EUR
Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Annexin A1 Antibody

V3736SAF-100UG NSJ Bioreagents 100 ug 349.3 EUR
Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Annexin A1 Antibody

V3741-100UG NSJ Bioreagents 100 ug 349.3 EUR
Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Annexin A1 Antibody

V3741-20UG NSJ Bioreagents 20 ug 153.3 EUR
Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Annexin A1 Antibody

V3741IHC-7ML NSJ Bioreagents 7 ml 349.3 EUR
Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Annexin A1 Antibody

V3741SAF-100UG NSJ Bioreagents 100 ug 349.3 EUR
Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Annexin A1 Antibody

V7283-100UG NSJ Bioreagents 100 ug 349.3 EUR
Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Annexin A1 Antibody

V7283-20UG NSJ Bioreagents 20 ug 153.3 EUR
Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Annexin A1 Antibody

V7283IHC-7ML NSJ Bioreagents 7 ml 349.3 EUR
Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Annexin A1 Antibody

V7283SAF-100UG NSJ Bioreagents 100 ug 349.3 EUR
Description: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Annexin V Antibody

RQ5261 NSJ Bioreagents 100ul 356.15 EUR
Description: The protein encoded by the ANXA5 gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. [RefSeq]

Annexin VI Antibody

RQ6590 NSJ Bioreagents 100ug 356.15 EUR
Description: Annexin A6 (ANXA6) is a member of a family of proteins that bind membrane or cytoskeleton in a Ca(2+)-dependent manner. These proteins are characterized by homologous amino acid sequences that are present in multiple copies in each protein. ANXA6 gene is assigned to 5q32-q34 by use of a cDNA clone to probe genomic DNA from rodent-human somatic cell hybrids and for in situ hybridization. The ANX6 gene is approximately 60 kb long and contains 26 exons. The genomic sequence at the 3-prime end does not contain a canonical polyadenylylation signal. Ca(2+)-dependent binding between CRHSP28 and ANXA6 is required for acinar cell membrane trafficking events and digestive enzyme secretion.

Annexin VI Antibody

RQ4425 NSJ Bioreagents 100 ug 356.15 EUR
Description: Annexin A6 (ANXA6) is a member of a family of proteins that bind membrane or cytoskeleton in a Ca(2+)-dependent manner. These proteins are characterized by homologous amino acid sequences that are present in multiple copies in each protein. ANXA6 gene is assigned to 5q32-q34 by use of a cDNA clone to probe genomic DNA from rodent-human somatic cell hybrids and for in situ hybridization. The ANX6 gene is approximately 60 kb long and contains 26 exons. The genomic sequence at the 3-prime end does not contain a canonical polyadenylylation signal. Ca(2+)-dependent binding between CRHSP28 and ANXA6 is required for acinar cell membrane trafficking events and digestive enzyme secretion.

Annexin A3 Antibody

RQ4892 NSJ Bioreagents 100ug 356.15 EUR
Description: Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

Annexin A6 Antibody

AF0116-100ul Affinity Biosciences 100ul 280 EUR

Annexin A6 Antibody

AF0116-200ul Affinity Biosciences 200ul 350 EUR

Annexin A7 Antibody

E38PA3769 EnoGene 100ul 225 EUR
Description: Available in various conjugation types.

Annexin A1 Antibody

E38PA4563 EnoGene 100ul 225 EUR
Description: Available in various conjugation types.

Annexin A1 Antibody

DF6254 Affinity Biosciences 100ul 280 EUR
Description: Human,Mouse,Rat

Annexin A2 Antibody

DF6468 Affinity Biosciences 100ul 280 EUR
Description: Human,Mouse,Rat

Annexin V Antibody

DF6580 Affinity Biosciences 100ul 280 EUR
Description: Human,Mouse,Rat

Annexin IV Antibody

DF8068 Affinity Biosciences 100ul 280 EUR
Description: Human,Mouse

Annexin A1 Antibody

AF5154-100ul Affinity Biosciences 100ul 280 EUR

Annexin A1 Antibody

AF5154-200ul Affinity Biosciences 200ul 350 EUR

Annexin A2 Antibody

AF5171-100ul Affinity Biosciences 100ul 280 EUR

Annexin A2 Antibody

AF5171-200ul Affinity Biosciences 200ul 350 EUR

Annexin A1 Antibody

AF5328-100ul Affinity Biosciences 100ul 280 EUR

Annexin A1 Antibody

AF5328-200ul Affinity Biosciences 200ul 350 EUR

Annexin A1 Antibody

DF6254-100ul Affinity Biosciences 100ul 280 EUR

Collectively, these data suggest that MEHP induces oxidative stress by disrupting the activities of antioxidant enzymes. This may lead to decreased expression of cell-cycle regulators and antiapoptotic regulators and increased expression of proapoptotic factors, which then may lead to inhibition of follicle growth.