Mono-(2-ethylhexyl)-phthalate (MEHP) affects ERK-dependent GDNF signalling in mouse stem-progenitor spermatogonia.

Many commercial and household products such as lubricants, cosmetics, plastics, and paint contain phthalates, in particular bis-(2-ethyhexyl)-phthalate (DEHP). As a consequence, phthalates have been found in a number of locations and foods (streambeds, household dust, bottled water and dairy products).

Epidemiological and animal studies analysing phthalate exposure in males provide evidence of degradation in sperm quality, associated to an increase in the incidence of genital birth defects and testicular cancers. In the testis, spermatogenesis is maintained throughout life by a small number of spermatogonial stem cells (SSCs) that self-renew or differentiate to produce adequate numbers of spermatozoa.

Disruption or alteration of SSC self-renewal induce decreased sperm count and sperm quality, or may potentially lead to testicular cancer. GDNF, or glial cell-line-derived neurotrophic factor, is a growth factor that is essential for the self-renewal of SSCs and continuous spermatogenesis. In the present study, the SSC-derived cell line C18-4 was used as a model for preliminary assessment of the effects of mono-(2-ethylhexyl)-phthalate (MEHP, main metabolite of DEHP) on spermatogonial stem cells.

ANK3 Antibody
37413-100ul	SAB	100ul	302.4 EUR
ANK3 Antibody
DF15475	Affbiotech	100ul	420 EUR
ANK3 Antibody
1-CSB-PA981926	Cusabio	380.40 EUR 292.80 EUR	100ul 50ul
Description: A polyclonal antibody against ANK3. Recognizes ANK3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100
ANK3 Antibody
1-CSB-PA619642LA01HU	Cusabio	380.40 EUR 402.00 EUR	100ug 50ug
Description: A polyclonal antibody against ANK3. Recognizes ANK3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200
ANK3 Conjugated Antibody
C37413	SAB	100ul	476.4 EUR
ANK3 Polyclonal Antibody
A69875	EpiGentek	754.26 EUR 117.70 EUR 293.70 EUR 470.80 EUR	100 ?g 20 ul 50 ul 100 ul
Ankyrin 3 (ANK3) Antibody
20-abx210627	Abbexa	493.20 EUR 360.00 EUR	100 ul 50 ul
Ankyrin G (ANK3) Antibody
abx445015-100ug	Abbexa	100 ug	627.6 EUR
Ankyrin 3 (ANK3) Antibody
20-abx334144	Abbexa	493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00 EUR	100 ug 1 mg 200 ug 20 ug 50 ug
Human ANK3 shRNA Plasmid
20-abx950201	Abbexa	961.20 EUR 1345.20 EUR	150 µg 300 µg
Mouse ANK3 shRNA Plasmid
20-abx969141	Abbexa	961.20 EUR 1345.20 EUR	150 µg 300 µg
ANK3 Antibody, HRP conjugated
1-CSB-PA619642LB01HU	Cusabio	380.40 EUR 402.00 EUR	100ug 50ug
Description: A polyclonal antibody against ANK3. Recognizes ANK3 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA
ANK3 Antibody, FITC conjugated
1-CSB-PA619642LC01HU	Cusabio	380.40 EUR 402.00 EUR	100ug 50ug
Description: A polyclonal antibody against ANK3. Recognizes ANK3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA
ANK3 Antibody, Biotin conjugated
1-CSB-PA619642LD01HU	Cusabio	380.40 EUR 402.00 EUR	100ug 50ug
Description: A polyclonal antibody against ANK3. Recognizes ANK3 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA
Ankyrin G (ANK3) Antibody (RPE)
abx444377-100ug	Abbexa	100 ug	693.6 EUR
Ankyrin 3 (ANK3) Antibody (HRP)
20-abx334695	Abbexa	493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00 EUR	100 ug 1 mg 200 ug 20 ug 50 ug
Ankyrin G (ANK3) Antibody (HRP)
abx443534-100ug	Abbexa	100 ug	678 EUR
Ankyrin G (ANK3) Antibody (ALP)
abx442412-100ug	Abbexa	100 ug	693.6 EUR
Ankyrin G (ANK3) Antibody (APC)
abx442693-100ug	Abbexa	100 ug	693.6 EUR
Ankyrin 3 (ANK3) Antibody (FITC)
20-abx334696	Abbexa	493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00 EUR	100 ug 1 mg 200 ug 20 ug 50 ug
Ankyrin G (ANK3) Antibody (FITC)
abx443253-100ug	Abbexa	100 ug	678 EUR
Ankyrin G (ANK3) Antibody (PerCP)
abx444096-100ug	Abbexa	100 ug	693.6 EUR
Ankyrin 3 (ANK3) Antibody (Biotin)
20-abx334697	Abbexa	493.20 EUR 2214.00 EUR 718.80 EUR 218.40 EUR 360.00 EUR	100 ug 1 mg 200 ug 20 ug 50 ug
Ankyrin G (ANK3) Antibody (Biotin)
abx442973-100ug	Abbexa	100 ug	693.6 EUR
Polyclonal ANK3 / ANKYRIN-G Antibody
APR11411G	Leading Biology	0.05mg	580.8 EUR
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human ANK3 / ANKYRIN-G . This antibody is tested and proven to work in the following applications:
Ankyrin G (ANK3) Antibody (Streptavidin)
abx444658-100ug	Abbexa	100 ug	693.6 EUR
Ank3 ORF Vector (Rat) (pORF)
ORF063393	ABM	1.0 ug DNA	3414 EUR
Ank3 ORF Vector (Rat) (pORF)
ORF063394	ABM	1.0 ug DNA	2496 EUR
ANK3 ORF Vector (Human) (pORF)
ORF015542	ABM	1.0 ug DNA	Ask for price
Ank3 ORF Vector (Mouse) (pORF)
ORF038598	ABM	1.0 ug DNA	1886.4 EUR
Ank3 ORF Vector (Mouse) (pORF)
ORF038599	ABM	1.0 ug DNA	1886.4 EUR
Ank3 ORF Vector (Mouse) (pORF)
ORF038600	ABM	1.0 ug DNA	1886.4 EUR
Ank3 ORF Vector (Mouse) (pORF)
ORF038601	ABM	1.0 ug DNA	1886.4 EUR
Ank3 ORF Vector (Mouse) (pORF)
ORF038602	ABM	1.0 ug DNA	1886.4 EUR
Ank3 ORF Vector (Mouse) (pORF)
ORF038603	ABM	1.0 ug DNA	607.2 EUR
Ank3 ORF Vector (Mouse) (pORF)
ORF038604	ABM	1.0 ug DNA	607.2 EUR
Ank3 ORF Vector (Mouse) (pORF)
ORF038605	ABM	1.0 ug DNA	1886.4 EUR
Ank3 ORF Vector (Mouse) (pORF)
ORF038606	ABM	1.0 ug DNA	607.2 EUR
Dog Ankyrin 3(ANK3) ELISA kit
E08A1450-192T	BlueGene	192 tests	1524 EUR
Description: A competitive ELISA for quantitative measurement of Canine Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Ankyrin 3(ANK3) ELISA kit
E08A1450-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A competitive ELISA for quantitative measurement of Canine Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Ankyrin 3(ANK3) ELISA kit
E08A1450-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A competitive ELISA for quantitative measurement of Canine Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Ankyrin 3(ANK3) ELISA kit
E02A1450-192T	BlueGene	192 tests	1524 EUR
Description: A competitive ELISA for quantitative measurement of Rat Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Ankyrin 3(ANK3) ELISA kit
E02A1450-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A competitive ELISA for quantitative measurement of Rat Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Ankyrin 3(ANK3) ELISA kit
E02A1450-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A competitive ELISA for quantitative measurement of Rat Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Ankyrin 3(ANK3) ELISA kit
E07A1450-192T	BlueGene	192 tests	1524 EUR
Description: A competitive ELISA for quantitative measurement of Porcine Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Ankyrin 3(ANK3) ELISA kit
E07A1450-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A competitive ELISA for quantitative measurement of Porcine Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Ankyrin 3(ANK3) ELISA kit
E07A1450-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A competitive ELISA for quantitative measurement of Porcine Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Ankyrin 3(ANK3) ELISA kit
E06A1450-192T	BlueGene	192 tests	1524 EUR
Description: A competitive ELISA for quantitative measurement of Goat Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Ankyrin 3(ANK3) ELISA kit
E06A1450-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A competitive ELISA for quantitative measurement of Goat Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Ankyrin 3(ANK3) ELISA kit
E06A1450-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A competitive ELISA for quantitative measurement of Goat Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Ankyrin 3(ANK3) ELISA kit
E01A1450-192T	BlueGene	192 tests	1524 EUR
Description: A competitive ELISA for quantitative measurement of Human Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Ankyrin 3(ANK3) ELISA kit
E01A1450-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A competitive ELISA for quantitative measurement of Human Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Ankyrin 3(ANK3) ELISA kit
E01A1450-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A competitive ELISA for quantitative measurement of Human Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Ankyrin 3(ANK3) ELISA kit
E03A1450-192T	BlueGene	192 tests	1524 EUR
Description: A competitive ELISA for quantitative measurement of Mouse Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Ankyrin 3(ANK3) ELISA kit
E03A1450-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A competitive ELISA for quantitative measurement of Mouse Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Ankyrin 3(ANK3) ELISA kit
E03A1450-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A competitive ELISA for quantitative measurement of Mouse Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Ankyrin- 3, ANK3 ELISA KIT
ELI-49314h	Lifescience Market	96 Tests	988.8 EUR
ANK3 Polyclonal Antibody, HRP Conjugated
A69876	EpiGentek	754.26 EUR 293.70 EUR 470.80 EUR	100 ?g 50 ul 100 ul
Ankyrin G (ANK3) Antibody (ATTO 390)
abx440164-100ug	Abbexa	100 ug	693.6 EUR
Ankyrin G (ANK3) Antibody (ATTO 488)
abx440445-100ug	Abbexa	100 ug	693.6 EUR
Ankyrin G (ANK3) Antibody (ATTO 565)
abx440726-100ug	Abbexa	100 ug	693.6 EUR
Ankyrin G (ANK3) Antibody (ATTO 594)
abx441007-100ug	Abbexa	100 ug	693.6 EUR
Ankyrin G (ANK3) Antibody (ATTO 633)
abx441288-100ug	Abbexa	100 ug	693.6 EUR
Ankyrin G (ANK3) Antibody (ATTO 655)
abx441569-100ug	Abbexa	100 ug	693.6 EUR
Ankyrin G (ANK3) Antibody (ATTO 680)
abx441850-100ug	Abbexa	100 ug	693.6 EUR
Ankyrin G (ANK3) Antibody (ATTO 700)
abx442131-100ug	Abbexa	100 ug	693.6 EUR
Monkey Ankyrin 3(ANK3) ELISA kit
E09A1450-192T	BlueGene	192 tests	1524 EUR
Description: A competitive ELISA for quantitative measurement of Monkey Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Ankyrin 3(ANK3) ELISA kit
E09A1450-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A competitive ELISA for quantitative measurement of Monkey Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Ankyrin 3(ANK3) ELISA kit
E09A1450-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A competitive ELISA for quantitative measurement of Monkey Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Ankyrin 3(ANK3) ELISA kit
E04A1450-192T	BlueGene	192 tests	1524 EUR
Description: A competitive ELISA for quantitative measurement of Rabbit Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Ankyrin 3(ANK3) ELISA kit
E04A1450-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A competitive ELISA for quantitative measurement of Rabbit Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Ankyrin 3(ANK3) ELISA kit
E04A1450-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A competitive ELISA for quantitative measurement of Rabbit Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
ANK3 Polyclonal Antibody, FITC Conjugated
A69877	EpiGentek	754.26 EUR 293.70 EUR 470.80 EUR	100 ?g 50 ul 100 ul
ANK3 Polyclonal Antibody, Biotin Conjugated
A69878	EpiGentek	754.26 EUR 293.70 EUR 470.80 EUR	100 ?g 50 ul 100 ul
Nori® Human ANK3 ELISA Kit
GR111480	Genorise Scientific	96-well	461 EUR
Ank3 sgRNA CRISPR Lentivector set (Rat)
K7175101	ABM	3 x 1.0 ug	406.8 EUR
ANK3 sgRNA CRISPR Lentivector set (Human)
K0086501	ABM	3 x 1.0 ug	406.8 EUR
Ank3 sgRNA CRISPR Lentivector set (Mouse)
K3930901	ABM	3 x 1.0 ug	406.8 EUR
Ankyrin G (ANK3) Antibody (PE/ATTO 594)
abx443815-100ug	Abbexa	100 ug	710.4 EUR
Guinea pig Ankyrin 3(ANK3) ELISA kit
E05A1450-192T	BlueGene	192 tests	1524 EUR
Description: A competitive ELISA for quantitative measurement of Guinea pig Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea pig Ankyrin 3(ANK3) ELISA kit
E05A1450-48	BlueGene	1 plate of 48 wells	624 EUR
Description: A competitive ELISA for quantitative measurement of Guinea pig Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea pig Ankyrin 3(ANK3) ELISA kit
E05A1450-96	BlueGene	1 plate of 96 wells	822 EUR
Description: A competitive ELISA for quantitative measurement of Guinea pig Ankyrin 3(ANK3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Ank3 3'UTR GFP Stable Cell Line
TU151793	ABM	1.0 ml	Ask for price
ANK3 3'UTR GFP Stable Cell Line
TU050759	ABM	1.0 ml	2799.6 EUR
Ank3 3'UTR GFP Stable Cell Line
TU250616	ABM	1.0 ml	Ask for price
ANK3 Protein Vector (Rat) (pPM-C-HA)
PV253572	ABM	500 ng	5095.2 EUR
ANK3 Protein Vector (Rat) (pPM-C-HA)
PV253576	ABM	500 ng	3930 EUR
ANK3 Protein Vector (Rat) (pPB-C-His)
PV253570	ABM	500 ng	5095.2 EUR
ANK3 Protein Vector (Rat) (pPB-N-His)
PV253571	ABM	500 ng	5095.2 EUR
ANK3 Protein Vector (Rat) (pPM-C-His)
PV253573	ABM	500 ng	5095.2 EUR
ANK3 Protein Vector (Rat) (pPB-C-His)
PV253574	ABM	500 ng	3930 EUR
ANK3 Protein Vector (Rat) (pPB-N-His)
PV253575	ABM	500 ng	3930 EUR
ANK3 Protein Vector (Rat) (pPM-C-His)
PV253577	ABM	500 ng	3930 EUR
ANK3 Protein Vector (Human) (pPM-C-HA)
PV062167	ABM	500 ng	Ask for price
ANK3 Protein Vector (Mouse) (pPM-C-HA)
PV154392	ABM	500 ng	3458.4 EUR
ANK3 Protein Vector (Mouse) (pPM-C-HA)
PV154396	ABM	500 ng	3888 EUR
ANK3 Protein Vector (Mouse) (pPM-C-HA)
PV154400	ABM	500 ng	3529.2 EUR
ANK3 Protein Vector (Mouse) (pPM-C-HA)
PV154404	ABM	500 ng	3854.4 EUR
ANK3 Protein Vector (Mouse) (pPM-C-HA)
PV154408	ABM	500 ng	3849.6 EUR
ANK3 Protein Vector (Mouse) (pPM-C-HA)
PV154412	ABM	500 ng	1278 EUR
ANK3 Protein Vector (Mouse) (pPM-C-HA)
PV154416	ABM	500 ng	1278 EUR
ANK3 Protein Vector (Mouse) (pPM-C-HA)
PV154420	ABM	500 ng	3816 EUR
ANK3 Protein Vector (Mouse) (pPM-C-HA)
PV154424	ABM	500 ng	1278 EUR
ANK3 Protein Vector (Human) (pPB-C-His)
PV062165	ABM	500 ng	Ask for price
ANK3 Protein Vector (Human) (pPB-N-His)
PV062166	ABM	500 ng	Ask for price
ANK3 Protein Vector (Human) (pPM-C-His)
PV062168	ABM	500 ng	Ask for price
ANK3 Protein Vector (Mouse) (pPB-C-His)
PV154390	ABM	500 ng	3458.4 EUR
ANK3 Protein Vector (Mouse) (pPB-N-His)
PV154391	ABM	500 ng	3458.4 EUR
ANK3 Protein Vector (Mouse) (pPM-C-His)
PV154393	ABM	500 ng	3458.4 EUR
ANK3 Protein Vector (Mouse) (pPB-C-His)
PV154394	ABM	500 ng	3888 EUR
ANK3 Protein Vector (Mouse) (pPB-N-His)
PV154395	ABM	500 ng	3888 EUR
ANK3 Protein Vector (Mouse) (pPM-C-His)
PV154397	ABM	500 ng	3888 EUR
ANK3 Protein Vector (Mouse) (pPB-C-His)
PV154398	ABM	500 ng	3529.2 EUR
ANK3 Protein Vector (Mouse) (pPB-N-His)
PV154399	ABM	500 ng	3529.2 EUR
ANK3 Protein Vector (Mouse) (pPM-C-His)
PV154401	ABM	500 ng	3529.2 EUR
ANK3 Protein Vector (Mouse) (pPB-C-His)
PV154402	ABM	500 ng	3854.4 EUR
ANK3 Protein Vector (Mouse) (pPB-N-His)
PV154403	ABM	500 ng	3854.4 EUR
ANK3 Protein Vector (Mouse) (pPM-C-His)
PV154405	ABM	500 ng	3854.4 EUR
ANK3 Protein Vector (Mouse) (pPB-C-His)
PV154406	ABM	500 ng	3849.6 EUR
ANK3 Protein Vector (Mouse) (pPB-N-His)
PV154407	ABM	500 ng	3849.6 EUR
ANK3 Protein Vector (Mouse) (pPM-C-His)
PV154409	ABM	500 ng	3849.6 EUR
ANK3 Protein Vector (Mouse) (pPB-C-His)
PV154410	ABM	500 ng	1278 EUR
ANK3 Protein Vector (Mouse) (pPB-N-His)
PV154411	ABM	500 ng	1278 EUR
ANK3 Protein Vector (Mouse) (pPM-C-His)
PV154413	ABM	500 ng	1278 EUR
ANK3 Protein Vector (Mouse) (pPB-C-His)
PV154414	ABM	500 ng	1278 EUR
ANK3 Protein Vector (Mouse) (pPB-N-His)
PV154415	ABM	500 ng	1278 EUR
ANK3 Protein Vector (Mouse) (pPM-C-His)
PV154417	ABM	500 ng	1278 EUR
ANK3 Protein Vector (Mouse) (pPB-C-His)
PV154418	ABM	500 ng	3816 EUR
ANK3 Protein Vector (Mouse) (pPB-N-His)
PV154419	ABM	500 ng	3816 EUR
ANK3 Protein Vector (Mouse) (pPM-C-His)
PV154421	ABM	500 ng	3816 EUR
ANK3 Protein Vector (Mouse) (pPB-C-His)
PV154422	ABM	500 ng	1278 EUR
ANK3 Protein Vector (Mouse) (pPB-N-His)
PV154423	ABM	500 ng	1278 EUR
ANK3 Protein Vector (Mouse) (pPM-C-His)
PV154425	ABM	500 ng	1278 EUR
ANK3 3'UTR Luciferase Stable Cell Line
TU000759	ABM	1.0 ml	2799.6 EUR
Ank3 3'UTR Luciferase Stable Cell Line
TU101793	ABM	1.0 ml	Ask for price
Ank3 3'UTR Luciferase Stable Cell Line
TU200616	ABM	1.0 ml	Ask for price
ANK3 Protein Vector (Human) (pPB-His-MBP)
PV321794	ABM	500 ng	Ask for price
ANK3 Protein Vector (Human) (pPB-His-GST)
PV321795	ABM	500 ng	Ask for price
Ank3 sgRNA CRISPR Lentivector (Rat) (Target 1)
K7175102	ABM	1.0 ug DNA	184.8 EUR
Ank3 sgRNA CRISPR Lentivector (Rat) (Target 2)
K7175103	ABM	1.0 ug DNA	184.8 EUR
Ank3 sgRNA CRISPR Lentivector (Rat) (Target 3)
K7175104	ABM	1.0 ug DNA	184.8 EUR
ANK3 sgRNA CRISPR Lentivector (Human) (Target 1)
K0086502	ABM	1.0 ug DNA	184.8 EUR
ANK3 sgRNA CRISPR Lentivector (Human) (Target 2)
K0086503	ABM	1.0 ug DNA	184.8 EUR
ANK3 sgRNA CRISPR Lentivector (Human) (Target 3)
K0086504	ABM	1.0 ug DNA	184.8 EUR
Ank3 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K3930902	ABM	1.0 ug DNA	184.8 EUR
Ank3 sgRNA CRISPR Lentivector (Mouse) (Target 2)
K3930903	ABM	1.0 ug DNA	184.8 EUR
Ank3 sgRNA CRISPR Lentivector (Mouse) (Target 3)
K3930904	ABM	1.0 ug DNA	184.8 EUR
ANK3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
LV658603	ABM	1.0 ug DNA	4719.6 EUR
ANK3 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)
LV658607	ABM	1.0 ug DNA	4719.6 EUR

Our data demonstrate that MEHP disrupts one of the known GDNF signalling pathways in these cells. MEHP induced a decrease of C18-4 cell viability in a time- and dose-dependent manner, as well as a disruption of ERK1/2 activation but not of SRC signalling. As a result, we observed a decrease of expression of the transcription factor FOS, which is downstream of the GDNF/ERK1/2 axis in these cells. Taken together, our data suggest that MEHP exposure affects SSC proliferation through inhibition of specific signalling molecules.