Mono(2-ethylhexyl) phthalate accelerates early folliculogenesis and inhibits steroidogenesis in cultured mouse whole ovaries and antral follicles.

Humans are ubiquitously uncovered to di(2-ethylhexyl) phthalate (DEHP), which is an environmental toxicant current in frequent client merchandise. DEHP doubtlessly targets the ovary via its metabolite mono(2-ethylhexyl) phthalate (MEHP). However, the direct results of MEHP on ovarian folliculogenesis and steroidogenesis, two processes important for reproductive and nonreproductive well being, are unknown.
The current research examined the hypotheses that MEHP instantly accelerates early folliculogenesis through overactivation of phosphatidylinositol 3-kinase (PI3K) signaling, a pathway that regulates primordial follicle quiescence and activation, and inhibits the synthesis of steroid hormones by lowering steroidogenic enzyme ranges. Neonatal ovaries from CD-1 mice have been cultured for six days with car management, DEHP, or MEHP (0.2-20 μg/ml) to evaluate the direct results on folliculogenesis and PI3K signaling. Further, antral follicles from grownup CD-1 mice have been cultured with car management or MEHP (0.1-10 μg/ml) for 24-96 h to ascertain the temporal results of MEHP on steroid hormones and steroidogenic enzymes. In the neonatal ovaries, MEHP, however not DEHP, decreased phosphatase and tensin homolog ranges and elevated phosphorylated protein kinase B ranges, resulting in a lower in the share of germ cells and a rise in the share of main follicles.
In the antral follicles, MEHP decreased the mRNA ranges of 17alpha-hydroxylase-17,20-desmolase, 17beta-hydroxysteroid dehydrogenase, and aromatase resulting in a lower in testosterone, estrone, and estradiol ranges. Collectively, MEHP mediates the impact of DEHP on accelerated folliculogenesis through overactivating PI3K signaling and inhibits steroidogenesis by lowering steroidogenic enzyme ranges.

ANNEXIN V:FITC ASSAY KIT (OKSA11265)

OKSA11265 Aviva Systems Biology 300 Tests 1375.2 EUR
Description: Description of target: ANNEXIN V:FITC ASSAY KIT;Species reactivity: Human;Application: FC;Assay info: ;Sensitivity:

ANNEXIN V:Biotin ASSAY KIT (OKSA11262)

OKSA11262 Aviva Systems Biology 100 Tests 944.4 EUR
Description: Description of target: ANNEXIN V:Biotin ASSAY KIT;Species reactivity: Human;Application: FC;Assay info: ;Sensitivity:

ANNEXIN V:Biotin ASSAY KIT (OKSA11264)

OKSA11264 Aviva Systems Biology 300 Tests 1375.2 EUR
Description: Description of target: ANNEXIN V:Biotin ASSAY KIT;Species reactivity: Human;Application: FC;Assay info: ;Sensitivity:

Dual Apoptosis Assay with NucView 488 Caspase-3 Substrate and CF594 Annexin V (50 assays)

30067 Biotium 1KIT 514.8 EUR
Description: Minimum order quantity: 1 unit of 1KIT

Annexin V, R-phycoerythrin conjugate (100 assays)

9-29045 Biotium
  • 178.80 EUR
  • 374.40 EUR
  • 100uL
  • 500uL
Description: Minimum order quantity: 1 unit of 500uL

Annexin V, Allophycocyanin crosslinked conjugate (100 assays)

9-29057 Biotium
  • 178.80 EUR
  • 374.40 EUR
  • 100uL
  • 500uL
Description: Minimum order quantity: 1 unit of 500uL

Cell Meter™ Annexin V Binding Apoptosis Assay Kit *Blue Fluorescence Excited at 405 nm*

22828 AAT Bioquest 100 Tests 222 EUR

Annexin V (PE)

abx090613-100tests Abbexa 100 tests 644.4 EUR

Annexin V PE

EXB0027 ExBio 100 tests 244.8 EUR

Annexin V (APC)

abx090615-100tests Abbexa 100 tests 718.8 EUR

Annexin V APC

EXB0028 ExBio 100 tests 244.8 EUR

Cell Meter™ Annexin V Binding Apoptosis Assay Kit *Green Fluorescence Excited at 405 nm*

22829 AAT Bioquest 100 Tests 222 EUR

Cell Meter™ Annexin V Binding Apoptosis Assay Kit *Orange Fluorescence Excited at 405 nm*

22830 AAT Bioquest 100 Tests 222 EUR

Annexin V (FITC)

abx090611-100tests Abbexa 100 tests 510 EUR

Annexin V FITC

EXB0024 ExBio 100 tests 244.8 EUR

Annexin V, CF770

29046 Biotium 25ug 410.4 EUR
Description: Minimum order quantity: 1 unit of 25ug

Annexin V, CF790

29047 Biotium 25ug 439.2 EUR
Description: Minimum order quantity: 1 unit of 25ug

Annexin V siRNA

20-abx900343 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

Annexin V siRNA

20-abx907673 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

Annexin V siRNA

20-abx907674 Abbexa
  • 661.20 EUR
  • 878.40 EUR
  • 15 nmol
  • 30 nmol

Annexin V antibody

70R-11770 Fitzgerald 100 ug 632.4 EUR
Description: Rabbit polyclonal Annexin V antibody

Annexin V antibody

70R-13691 Fitzgerald 100 ug 386.4 EUR
Description: Affinity purified Rabbit polyclonal Annexin V antibody

Annexin V Antibody

49376-100ul SAB 100ul 399.6 EUR

Annexin V Antibody

49376-50ul SAB 50ul 286.8 EUR

Annexin V antibody

10R-7939 Fitzgerald 100 ug 516 EUR
Description: Mouse monoclonal Annexin V antibody

Annexin V antibody

20R-1522 Fitzgerald 100 ug 781.2 EUR
Description: Rabbit polyclonal Annexin V antibody

Annexin V Antibody

3357-100 Biovision each 464.4 EUR

Annexin V Antibody

3357-30T Biovision each 175.2 EUR

Annexin V Antibody

DF6580 Affbiotech 200ul 420 EUR

Annexin V Antibody

F49706-0.08ML NSJ Bioreagents 0.08 ml 140.25 EUR
Description: Annexin 5 belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII.

Annexin V Antibody

F49706-0.4ML NSJ Bioreagents 0.4 ml 322.15 EUR
Description: Annexin 5 belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII.

Annexin V Antibody

F49707-0.08ML NSJ Bioreagents 0.08 ml 140.25 EUR
Description: Annexin 5 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. [UniProt]

Annexin V Antibody

F49707-0.4ML NSJ Bioreagents 0.4 ml 322.15 EUR
Description: Annexin 5 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. [UniProt]

Annexin V antibody

PAab09988 Lifescience Market 100 ug 463.2 EUR

Annexin V Antibody

RQ5261 NSJ Bioreagents 100ul 356.15 EUR
Description: The protein encoded by the ANXA5 gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. [RefSeq]

Annexin V Antibody

R30176 NSJ Bioreagents 100 ug 356.15 EUR
Description: Annexin V is also know as endonnexin II (ENX2),or placental protein 4 (PP4). It is a member of the family of Ca(2+)-dependent phospholipid binding proteins, known as annexins. It bind to the phospholipids that are preferentially located on the cytosolic face of the plasma membrane. Annexin V has a relative molecular weight of about 35,000. The gene lies on mouse chromosome 3 in close linkage with the fibroblast growth factor 2(basic) gene and is syntenic with other genes known to have orthologous counterparts on human chromosome 4q. The cDNA encoded a protein of 320 amino acid residues. A single mRNA, approximately 1.6 kb long, was found to be expressed in human cell lines and placenta. It is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

Annexin V Antibody

R31475 NSJ Bioreagents 100 ug 356.15 EUR
Description: Annexin V or A5 has been proposed to play a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with prothrombin and also to inhibit the activity of phospholipase A1. This protein is an anticoagulant protein, it can form a shield around negatively-charged phospholipid molecules, the formation of an Annexin V shield blocks the entry of phospholipids into coagulation (clotting) reactions. Annexin AV can also act as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

Annexin V, sulforhodamine 101 conjugate (Texas-Red Annexin V)

29002 Biotium 0.5ML 332.4 EUR
Description: Minimum order quantity: 1 unit of 0.5ML

Annexin V, Recombinant

20014 AAT Bioquest 100 ug 222 EUR

Annexin V, Recombinant

20015 AAT Bioquest 1 mg 1509 EUR

Cell Meter™ Annexin V Binding Apoptosis Assay Kit *Red Fluorescence Optimized for Flow Cytometry*

22826 AAT Bioquest 100 Tests 222 EUR

Cell Meter™ Annexin V Binding Apoptosis Assay Kit *Green Fluorescence Optimized for Flow Cytometry*

22824 AAT Bioquest 100 Tests 222 EUR

Cell Meter™ Annexin V Binding Apoptosis Assay Kit *Orange Fluorescence Optimized for Flow Cytometry*

22825 AAT Bioquest 100 Tests 222 EUR

Annexin V ELISA kit

55R-IB49646 Fitzgerald 96 wells 1413.6 EUR
Description: ELISA kit for the detection of Annexin V in the research laboratory

Annexin V ELISA kit

55R-ORG643 Fitzgerald 96 wells 541.2 EUR
Description: ELISA kit for the detection of Annexin V in the research laboratory

Annexin V Dyomics 647

EXB0023 ExBio 100 tests 266.4 EUR

Cell Meter™ Annexin V Binding Apoptosis Assay Kit *Deep Red Fluorescence Optimized for Flow Cytometry*

22827 AAT Bioquest 100 Tests 222 EUR

Annexin V-PE Reagent

1014-1000 Biovision each 1358.4 EUR

Annexin V-PE Reagent

1014-200 Biovision each 483.6 EUR

Active Annexin V (ANXA5)

4-APA259Ra01 Cloud-Clone
  • 743.62 EUR
  • 322.80 EUR
  • 2458.56 EUR
  • 899.52 EUR
  • 1679.04 EUR
  • 573.60 EUR
  • 5966.40 EUR
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Annexin V expressed in: E.coli

Annexin V-Cy5 Reagent

1013-1000 Biovision each 1358.4 EUR

Annexin V-Cy5 Reagent

1013-200 Biovision each 483.6 EUR

Annexin V-Cy3 Reagent

1002-1000 Biovision each 1358.4 EUR

Annexin V-Cy3 Reagent

1002-200 Biovision each 483.6 EUR

Annexin V, FITC Labeled

20030 AAT Bioquest 100 tests 222 EUR

Annexin V-FITC Reagent

1001-1000 Biovision each 1495.2 EUR

Annexin V-FITC Reagent

1001-200 Biovision each 529.2 EUR

Annexin V-EGFP Reagent

1004-1000 Biovision each 1358.4 EUR

Annexin V-EGFP Reagent

1004-200 Biovision each 483.6 EUR

anti- Annexin V antibody

FNab09988 FN Test 100µg 658.5 EUR
Description: Antibody raised against Annexin V

anti- Annexin V antibody

FNab00436 FN Test 100µg 606.3 EUR
Description: Antibody raised against Annexin V

anti- Annexin V antibody

FNab00437 FN Test 100µg 606.3 EUR
Description: Antibody raised against Annexin V

Recombinant human Annexin A5/Annexin V/ANXA5 Protein

RP01180 Abclonal 10 μg 186 EUR

Annexin V, FITC conjugate

29001 Biotium 0.5ML 332.4 EUR
Description: Minimum order quantity: 1 unit of 0.5ML

Annexin V (ANXA5) Antibody

abx230436-100ug Abbexa 100 ug 577.2 EUR

Annexin V (ANXA5) Antibody

abx230437-100ug Abbexa 100 ug 577.2 EUR

Annexin V (ANXA5) Antibody

20-abx109257 Abbexa
  • 493.20 EUR
  • 2214.00 EUR
  • 718.80 EUR
  • 218.40 EUR
  • 360.00 EUR
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Annexin V (ANXA5) Antibody

20-abx109540 Abbexa
  • 493.20 EUR
  • 2214.00 EUR
  • 718.80 EUR
  • 218.40 EUR
  • 360.00 EUR
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Annexin V-Cy3 conjugate

20065 AAT Bioquest 100 Tests 222 EUR

Annexin V-Cy5 conjugate

20066 AAT Bioquest 100 Tests 222 EUR

Annexin V-Cy5.5 conjugate

20067 AAT Bioquest 100 Tests 222 EUR

Annexin V-Cy7 conjugate

20068 AAT Bioquest 100 Tests 222 EUR

Annexin V (ANXA5) Antibody

abx037408-100ug Abbexa 100 ug 469.2 EUR

Annexin V (ANXA5) Antibody

abx038319-100ug Abbexa 100 ug 469.2 EUR

Annexin V (ANXA5) Antibody

20-abx001443 Abbexa
  • 493.20 EUR
  • 710.40 EUR
  • 218.40 EUR
  • 376.80 EUR
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Annexin V Binding Buffer

abx090621-100tests Abbexa 100 tests 343.2 EUR

Annexin V (ANXA5) Antibody

abx412125-01mg Abbexa 0.1 mg 1078.8 EUR

Annexin V (ANXA5) Antibody

abx414511-01mg Abbexa 0.1 mg 526.8 EUR

Annexin V (ANXA5) Antibody

20-abx110998 Abbexa
  • 878.40 EUR
  • 477.60 EUR
  • 150 ul
  • 50 ul

Annexin V (ANXA5) Antibody

20-abx121016 Abbexa
  • 360.00 EUR
  • 526.80 EUR
  • 226.80 EUR
  • 100 ul
  • 200 ul
  • 30 ul

Annexin V (ANXA5) Antibody

abx032878-400ul Abbexa 400 ul 627.6 EUR

Annexin V (ANXA5) Antibody

abx032878-80l Abbexa 80 µl 343.2 EUR

Annexin V (ANXA5) Antibody

abx032879-400ul Abbexa 400 ul 627.6 EUR

Annexin V (ANXA5) Antibody

abx032879-80l Abbexa 80 µl 343.2 EUR

Annexin V, CF647 conjugate

29003 Biotium 0.5ML 368.4 EUR
Description: Minimum order quantity: 1 unit of 0.5ML

Annexin V, CF555 conjugate

29004 Biotium 0.5ML 368.4 EUR
Description: Minimum order quantity: 1 unit of 0.5ML

Annexin V, CF750 conjugate

29006 Biotium 25ug 410.4 EUR
Description: Minimum order quantity: 1 unit of 25ug

Annexin V, CF680 conjugate

29007 Biotium 25ug 410.4 EUR
Description: Minimum order quantity: 1 unit of 25ug

Annexin V, CF633 conjugate

29008 Biotium 0.5ML 368.4 EUR
Description: Minimum order quantity: 1 unit of 0.5ML

Annexin V, CF568 conjugate

29010 Biotium 0.5ML 368.4 EUR
Description: Minimum order quantity: 1 unit of 0.5ML

Annexin V, CF594 conjugate

29011 Biotium 0.5ML 368.4 EUR
Description: Minimum order quantity: 1 unit of 0.5ML

Annexin V, CF350 conjugate

29012 Biotium 0.5mL 368.4 EUR
Description: Minimum order quantity: 1 unit of 0.5mL

Annexin V, CF800 conjugate

29078 Biotium 25ug 440.4 EUR
Description: Minimum order quantity: 1 unit of 25ug

Annexin V, CF700 conjugate

29082 Biotium 25ug 428.4 EUR
Description: Minimum order quantity: 1 unit of 25ug

Annexin V, CF450 conjugate

29083 Biotium 0.5mL 363.6 EUR
Description: Minimum order quantity: 1 unit of 0.5mL

Annexin V-Biotin Reagent

1003-100 Biovision each 444 EUR

Annexin V-Biotin Reagent

1003-1000 Biovision each 2865.6 EUR

Annexin V, CF405M conjugate

29009 Biotium 0.5ML 368.4 EUR
Description: Minimum order quantity: 1 unit of 0.5ML

Annexin V, Biotin conjugate

29013 Biotium 0.5mL 368.4 EUR
Description: Minimum order quantity: 1 unit of 0.5mL

Annexin V, CF640R conjugate

29014 Biotium 0.5mL 368.4 EUR
Description: Minimum order quantity: 1 unit of 0.5mL

Annexin V, CF660R conjugate

29069 Biotium 0.5mL 373.2 EUR
Description: Minimum order quantity: 1 unit of 0.5mL

Annexin V, CF680R conjugate

29070 Biotium 25ug 412.8 EUR
Description: Minimum order quantity: 1 unit of 25ug

Annexin V Blocking Peptide

3357BP-50 Biovision each 183.6 EUR

Annexin V Blocking Peptide

33R-10472 Fitzgerald 50 ug 418.8 EUR
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of Annexin V antibody, catalog no. 20R-1522

Annexin V Blocking Peptide

33R-10724 Fitzgerald 50 ug 202.8 EUR
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of Annexin V antibody, catalog no. 70R-11770

Annexin V Blocking Peptide

20-abx161016 Abbexa
  • 326.40 EUR
  • 493.20 EUR
  • 1 mg
  • 5 mg

Annexin V, CF488A conjugate

29005 Biotium 0.5ML 368.4 EUR
Description: Minimum order quantity: 1 unit of 0.5ML

Annexin V, human recombinant

1005-100 Biovision each 385.2 EUR

Annexin V, human recombinant

1005-1000 Biovision each 2440.8 EUR

Annexin V, human recombinant

1005-5000 Biovision each 6903.6 EUR

Annexin V-Biotin conjugate

20018 AAT Bioquest 100 tests 222 EUR

Annexin V, PacBlue conjugate

20089 AAT Bioquest 100 tests 222 EUR

Annexin V, human recombinant

K2064-.1 ApexBio 100 µg 435.6 EUR
Description: Annexin V is a cellular protein, which plays important roles in the inhibition of the activity of phospholipase A1 and blood coagulation by competing for phosphatidylserine (PS) binding sites with prothrombin

Annexin V, human recombinant

K2064-1 ApexBio 1 mg 2815.2 EUR
Description: Annexin V is a cellular protein, which plays important roles in the inhibition of the activity of phospholipase A1 and blood coagulation by competing for phosphatidylserine (PS) binding sites with prothrombin

Annexin V, human recombinant

K2064-5 ApexBio 5 mg 8402.4 EUR
Description: Annexin V is a cellular protein, which plays important roles in the inhibition of the activity of phospholipase A1 and blood coagulation by competing for phosphatidylserine (PS) binding sites with prothrombin

Recombinant Annexin V (ANXA5)

4-RPA259Hu02 Cloud-Clone
  • 571.58 EUR
  • 276.00 EUR
  • 1813.44 EUR
  • 684.48 EUR
  • 1248.96 EUR
  • 458.40 EUR
  • 4353.60 EUR
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Annexin V expressed in: E.coli

Annexin V Polyclonal Antibody

27222-100ul SAB 100ul 302.4 EUR

Annexin V Polyclonal Antibody

27222-50ul SAB 50ul 224.4 EUR

Annexin V Recombinant Protein

90-218 ProSci 100 ug 437.1 EUR
Description: Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e. g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.

Annexin V Conjugated Antibody

C49376 SAB 100ul 476.4 EUR

Dog Annexin V ELISA kit

E08A0209-192T BlueGene 192 tests 1524 EUR
Description: A sandwich ELISA for quantitative measurement of Canine Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Annexin V ELISA kit

E08A0209-48 BlueGene 1 plate of 48 wells 624 EUR
Description: A sandwich ELISA for quantitative measurement of Canine Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Annexin V ELISA kit

E08A0209-96 BlueGene 1 plate of 96 wells 822 EUR
Description: A sandwich ELISA for quantitative measurement of Canine Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Annexin V ELISA kit

E08A0593-192T BlueGene 192 tests 1524 EUR
Description: A competitive ELISA for quantitative measurement of Canine Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Annexin V ELISA kit

E08A0593-48 BlueGene 1 plate of 48 wells 624 EUR
Description: A competitive ELISA for quantitative measurement of Canine Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Annexin V ELISA kit

E08A0593-96 BlueGene 1 plate of 96 wells 822 EUR
Description: A competitive ELISA for quantitative measurement of Canine Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Annexin V ELISA kit

E07A0593-192T BlueGene 192 tests 1524 EUR
Description: A competitive ELISA for quantitative measurement of Porcine Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Annexin V ELISA kit

E07A0593-48 BlueGene 1 plate of 48 wells 624 EUR
Description: A competitive ELISA for quantitative measurement of Porcine Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Annexin V ELISA kit

E07A0593-96 BlueGene 1 plate of 96 wells 822 EUR
Description: A competitive ELISA for quantitative measurement of Porcine Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Annexin V ELISA kit

E07A0209-192T BlueGene 192 tests 1524 EUR
Description: A sandwich ELISA for quantitative measurement of Porcine Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Annexin V ELISA kit

E07A0209-48 BlueGene 1 plate of 48 wells 624 EUR
Description: A sandwich ELISA for quantitative measurement of Porcine Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Annexin V ELISA kit

E07A0209-96 BlueGene 1 plate of 96 wells 822 EUR
Description: A sandwich ELISA for quantitative measurement of Porcine Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Annexin V ELISA kit

E02A0593-192T BlueGene 192 tests 1524 EUR
Description: A competitive ELISA for quantitative measurement of Rat Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Annexin V ELISA kit

E02A0593-48 BlueGene 1 plate of 48 wells 624 EUR
Description: A competitive ELISA for quantitative measurement of Rat Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Annexin V ELISA kit

E02A0593-96 BlueGene 1 plate of 96 wells 822 EUR
Description: A competitive ELISA for quantitative measurement of Rat Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Annexin V ELISA kit

E02A0209-192T BlueGene 192 tests 1524 EUR
Description: A sandwich ELISA for quantitative measurement of Rat Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Annexin V ELISA kit

E02A0209-48 BlueGene 1 plate of 48 wells 624 EUR
Description: A sandwich ELISA for quantitative measurement of Rat Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Annexin V ELISA kit

E02A0209-96 BlueGene 1 plate of 96 wells 822 EUR
Description: A sandwich ELISA for quantitative measurement of Rat Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Annexin V ELISA kit

E06A0209-192T BlueGene 192 tests 1524 EUR
Description: A sandwich ELISA for quantitative measurement of Goat Annexin V in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mono(2-ethylhexyl) phthalate accelerates early folliculogenesis and inhibits steroidogenesis in cultured mouse whole ovaries and antral follicles.
Mono(2-ethylhexyl) phthalate accelerates early folliculogenesis and inhibits steroidogenesis in cultured mouse whole ovaries and antral follicles.

The results of intraplantar and intrathecal botulinum toxin sort B on tactile allodynia in mono and polyneuropathy in the mouse.

BACKGROUND
Mononeuropathies (MNs: nerve ligation) and polyneuropathies (PNs: cisplatin) produce unilateral and bilateral tactile allodynia, respectively. We examined the consequences of intraplantar (IPLT) and intrathecal (IT) botulinum toxin B (BoNT-B) on this allodynia.
METHODS
Mice (male c57Bl/6) have been ready with an L5 nerve ligation. Others obtained cisplatin (IP 2.Three mg/kg/d, each different day for six injections). Saline and BoNT-B have been administered via the IPLT or IT route. We examined mechanical allodynia (von Frey hairs) earlier than and at intervals after BoNT. As a management, we injected IPLT BoNT-B handled with dithiothreitol to cleave heavy chain from gentle chain. We measured motor operate utilizing acute thermal escape and sensorimotor assessments.
RESULTS
MN and PN mice confirmed a persistent ipsilateral and bilateral allodynia, respectively. IPLT BoNT-B resulted in an ipsilateral dorsal horn discount in the synaptic protein goal of BoNT-B (vesicle-associated membrane protein) and a long-lasting (as much as roughly 17 days) reversal of allodynia in PN and MN fashions. The predominant impact after IPLT supply was ipsilateral to IPLT BoNT. The results of IPLT BoNT-B in MN mice have been blocked by prior discount of BoNT-B with dithiothreitol.
IT BoNT-B in mice with PN resulted in a bilateral reversal of allodynia. With these dosing parameters, hind paw putting and stepping reflexes have been unaltered, and there have been no modifications in thermal escape latencies. After cisplatin, dorsal root ganglions displayed will increase in activation transcription issue 3, which have been diminished by IT, however not IPLT BoNT-B.
CONCLUSIONS
BoNT-B given IPLT and IT yields a long-lasting attenuation of the allodynia in mice displaying MN and PN allodynia.

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